Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.31 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12738654 | 0.99 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL2136799 | 0.89 | HPGD (0.40) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL2141054 | 0.84 | RXRA (0.32) | CYP3A4MAPT | |
| SCHEMBL6884754 | 0.79 | ELANE (0.30) | — | |
| SCHEMBL12738651 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL2137332 | 0.74 | — | — | |
| SCHEMBL7071712 | 0.72 | — | — | |
| SCHEMBL3367137 | 0.70 | PPARA (0.34) | ALDH1A1LMNA | |
| SCHEMBL7070810 | 0.70 | — | — | |
| SCHEMBL7071716 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902368-B2 | Cationic substituted 2,2,6,6-tetraalkylpiperidinyl alkoxyamines | BASF SE (DE) | 2011-03-08 | — | — | US | disclosed |
| US-20090306382-A1 | CATIONIC ALKOXYAMINES | MUEHLEBACH ANDREAS | 2009-12-10 | — | — | US | disclosed |
| EP-1515950-B1 | CATIONIC ALKOXYAMINES AND THEIR USE IN PRODUCING NANO PARTICLES FROM NATURAL OR SYNTHETIC CLAYS | BASF SE (DE) | 2009-12-02 | — | — | EP | disclosed |
| US-7595359-B2 | Organoclays; coatings, sealants, caulks, adhesives and plastic additives | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-09-29 | — | — | US | disclosed |
| US-20050215691-A1 | Cationic alkoxyamines and their use in producing nano particles from natural or synthetic clays | BASF SE (DE) | 2005-09-29 | — | — | US | disclosed |
| EP-1515950-A1 | CATIONIC ALKOXYAMINES AND THEIR USE IN PRODUCING NANO PARTICLES FROM NATURAL OR SYNTHETIC CLAYS | Ciba SC Holding AG (CH) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004000809-A1 | CATIONIC ALKOXYAMINES AND THEIR USE IN PRODUCING NANO PARTICLES FROM NATURAL OR SYNTHETIC CLAYS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306382-A1 | CATIONIC ALKOXYAMINES | ALKBH2, ALKBH3, ALKBH5 | ALDH1A1 2271/4885KMT2A 230/4885MEN1 3251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.