Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | ADA | P00813 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19325462 | 0.88 | CYP1A2 (0.67) | CYP1A2LMNAALDH1A1ALBMAPK1 | |
| SCHEMBL3065891 | 0.82 | ALDH1A1 (0.54) | CYP1A2LMNAALDH1A1ALBMAPK1 | |
| SCHEMBL6692360 | 0.81 | CYP1A2 (0.60) | CYP1A2LMNAALDH1A1ALBMAPK1 | |
| SCHEMBL6858256 | 0.81 | CYP1A2 (0.45) | CYP1A2LMNAPNPTP53HTT | |
| SCHEMBL21362298 | 0.79 | ALDH1A1 (0.64) | CYP1A2LMNAALDH1A1ALBMAPK1 | |
| SCHEMBL3162 | 0.79 | ALDH1A1 (0.70) | CYP1A2LMNAALDH1A1ALBMAPK1 | |
| SCHEMBL13833316 | 0.79 | ALDH1A1 (0.70) | CYP1A2LMNAALDH1A1ALBMAPK1 | |
| SCHEMBL16695889 | 0.79 | ALDH1A1 (0.70) | CYP1A2LMNAALDH1A1ALBMAPK1 | |
| SCHEMBL8104283 | 0.79 | ALDH1A1 (0.70) | CYP1A2LMNAALDH1A1ALBMAPK1 | |
| SCHEMBL19325461 | 0.79 | ALDH1A1 (0.70) | CYP1A2LMNAALDH1A1ALBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046328-A2 | PYRIDINONE DIKETO ACIDS: INHIBITORS OF HIV REPLICATION IN COMBINATION THERAPY | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2009-04-15 | — | — | EP | claimed |
| WO-2008010953-A2 | PYRIDINONE DIKETO ACIDS: INHIBITORS OF HIV REPLICATION IN COMBINATION THERAPY | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2008-01-24 | — | — | WO | claimed |
| EP-0350287-A2 | Lipid derivatives of antiviral nucleosides, liposomal incorporation and method of use | NeXstar Pharmaceuticals, Inc. (US) | 1990-01-10 | — | — | EP | claimed |
| EP-1974026-A2 | MUTANT DEOXYADENOSINE KINASE ENZYMES AND THEIR USE | ZGene A/S (DK) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007079753-A2 | MUTANT DEOXYADENOSINE KINASE ENZYMES AND THEIR USE | ZGENE A/S (DK) | 2007-07-19 | — | — | WO | disclosed |