Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13178886 | 0.83 | FFAR4 (0.43) | L3MBTL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4799391 | 0.81 | PYCR1 (0.43) | L3MBTL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8256542 | 0.80 | KDM4E (0.41) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL6603605 | 0.79 | APLNR (0.44) | CYP1A2 | |
| SCHEMBL755548 | 0.79 | PTPN1 (0.39) | L3MBTL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1145658 | 0.78 | KDM4E (0.51) | L3MBTL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10817318 | 0.78 | AMY1A (0.42) | L3MBTL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL19859281 | 0.78 | IDO1 (0.41) | L3MBTL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13327165 | 0.77 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18570745 | 0.77 | KDM4E (0.40) | L3MBTL1ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |