SCHEMBL20833591

SCHEMBL20833591

Cn1cc(I)nc1C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20833588 0.79 NPSR1 (0.39) L3MBTL1
SCHEMBL20833586 0.77 KMT2A (0.33)
SCHEMBL21362773 0.77 PTGS1 (0.39) L3MBTL1TDP1
SCHEMBL10423801 0.77 ALDH1A1 (0.34) L3MBTL1
SCHEMBL17006966 0.75 RXFP1 (0.34) L3MBTL1
SCHEMBL781347 0.75 GABRP (0.37) L3MBTL1
Hydrochloric Acid SCHEMBL28743230 0.73 GABRP (0.36) L3MBTL1
SCHEMBL16691890 0.72 ALDH1A1 (0.37)
SCHEMBL27164122 0.72 L3MBTL1 (0.36) L3MBTL1
SCHEMBL20833587 0.71 BRD4 (0.51) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190084928-A1 METHOD FOR PRODUCING NITROGEN-CONTAINING AROMATIC AMIDE, METHOD FOR PRODUCING PYRROLE-IMIDAZOLE POLYAMIDE, AND COMPOUND NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) 2019-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190084928-A1 METHOD FOR PRODUCING NITROGEN-CONTAINING AROMATIC AMIDE, METHOD FOR PRODUCING PYRROLE-IMIDAZOLE POLYAMIDE, AND COMPOUND NIT2, NAAA, NOS2 L3MBTL1 4727/4885TDP1 2249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.