Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22072005 | 0.68 | — | — | |
| SCHEMBL6509907 | 0.68 | ALOX15 (0.67) | ALOX15TSHRHIF1AMCL1TDP1 | |
| SCHEMBL2474863 | 0.68 | — | — | |
| SCHEMBL21972972 | 0.67 | MEN1 (0.40) | TSHRTDP1KDM4ELMNAALDH1A1 | |
| SCHEMBL20829148 | 0.65 | CYP19A1 (0.40) | TSHRMCL1TDP1KDM4EALDH1A1 | |
| SCHEMBL22212825 | 0.64 | KMT2A (0.40) | TSHRTDP1KDM4ELMNAALDH1A1 | |
| SCHEMBL23586344 | 0.62 | NPC1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL22296632 | 0.62 | L3MBTL1 (0.54) | KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL23586302 | 0.61 | NPC1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL19957846 | 0.61 | POLB (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019174277-A1 | PHOSPHOETHANOLAMINE TRANSFERASE INHIBITORS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2019-09-19 | — | — | WO | disclosed |