Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929809 | 0.90 | LMNA (0.44) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL7938746 | 0.86 | MEN1 (0.42) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL2750185 | 0.82 | MEN1 (0.61) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL11153839 | 0.81 | MEN1 (0.55) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL11153841 | 0.81 | MEN1 (0.55) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL10284708 | 0.81 | GAA (0.58) | KMT2AGAAALDH1A1LMNA | |
| SCHEMBL28273578 | 0.81 | ALDH1A1 (0.51) | GAAALDH1A1 | |
| SCHEMBL11150992 | 0.80 | MEN1 (0.59) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL9175588 | 0.80 | MEN1 (0.59) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL956201 | 0.80 | MEN1 (0.59) | MEN1KMT2AHDAC8HDAC6EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150191607-A1 | Anti-fouling Paints and Coatings | REACTIVE SURFACES, LTD (US) | 2015-07-09 | — | — | US | disclosed |
| US-20140196631-A1 | VISUAL ASSAYS FOR COATINGS INCORPORATING BIOACTIVE ENZYMES FOR CATALYTIC FUNCTIONS | REACTIVE SURFACE, LTD. (US) | 2014-07-17 | — | — | US | disclosed |
| EP-1719762-B1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | disclosed |
| US-20120097194-A1 | Polymeric Coatings Incorporating Bioactive Enzymes for Catalytic Function | REACTIVE SURFACES, LTD. (US) | 2012-04-26 | — | — | US | disclosed |
| US-20110250626-A1 | Visual Assays for Coatings Incorporating Bioactive Enzymes for Catalytic Functions | REACTIVE SURFACES, LTD. (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110240064-A1 | Polymeric Coatings Incorporating Bioactive Enzymes for Cleaning a Surface | REACTIVE SURFACES, LTD. (US) | 2011-10-06 | — | — | US | disclosed |
| US-20100210745-A1 | Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes | REACTIVE SURFACES, LTD. (US) | 2010-08-19 | — | — | US | disclosed |
| WO-2007018376-A1 | PRODUCING METHOD FOR CERIUM-BASED GLASS POLISHING MATERIAL AND METHOD FOR USING THE SAME | JOUNG IN (KR) | 2007-02-15 | — | — | WO | disclosed |
| WO-2000040663-A1 | ADHESION PROMOTERS | LOCTITE (R & D) LIMITED (IE) | 2000-07-13 | — | — | WO | disclosed |
| US-4410530-A | CARDIO-SELECTIVE B-RECEPTOR BLOCKING AGENTS AND STIMULANTS | CIBA-GEIGY CORPORATION (US) | 1983-10-18 | — | — | US | disclosed |
| US-4348427-A | Coating method and composition | ANIC, S.P.A. (IT) | 1982-09-07 | — | — | US | disclosed |
| US-4251619-A | Process for forming photo-polymeric image | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1981-02-17 | — | — | US | disclosed |
| US-4195090-A | ADRENERGIC BLOCKING AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-03-25 | — | — | US | disclosed |
| US-4115575-A | CARDIOVASCULAR DISORDERS | CIBA-GEIGY CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |