SCHEMBL7938746

SCHEMBL7938746

C=CNC(=O)Cc1cccc(CC(=O)NC=C)c1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
AOC2 O75106 1/20 0.41
ALDH1A1 P00352 2/20 0.41
EPHX2 P34913 2/20 0.40
KCNH2 Q12809 1/20 0.40
MAPT P10636 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
EGFR P00533 3/20 0.39
ERBB2 P04626 3/20 0.39
GLS O94925 1/20 0.39
SELP P16109 1/20 0.39
SELE P16581 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2136285 0.86 MEN1 (0.59) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL7929809 0.84 LMNA (0.44) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL7929831 0.81 GAA (0.47) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL21566634 0.80 KDM4E (0.55) ALDH1A1MAPTGAAHPGD
SCHEMBL28273578 0.76 ALDH1A1 (0.51) ALDH1A1MAPTGAAGLS
SCHEMBL10284708 0.76 GAA (0.58) KMT2AALDH1A1GAAEGFRERBB2
SCHEMBL7194491 0.74 AOC2 (0.67) MEN1KMT2AHDAC8HDAC6AOC2
SCHEMBL11631649 0.68 ALDH1A1 (0.54) ALDH1A1KCNH2MAPTGAAHPGD
SCHEMBL2748652 0.68 POLB (0.56) MEN1KMT2AHDAC6ALDH1A1
SCHEMBL2750185 0.68 MEN1 (0.61) MEN1KMT2AHDAC8HDAC6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0473881-B1 Liquid absorption agent SHOWA DENKO KK (JP) 2001-11-07 EP disclosed
US-5788950-A Method for the synthesis of mixed metal oxide powders SHOWA DENKO K.K. (JP) 1998-08-04 US disclosed
US-5744118-A MIXING ABSORBENT RESIN AND METAL SALTS, SWELLING AND GELATION, ADJUSTMENT OF PH, PYROLYSIS AND ROASTING SHOWA DENKO K.K. (JP) 1998-04-28 US disclosed
EP-0510246-B1 Use of fine particulate crosslinked type n-vinylamide resin microgel SHOWA DENKO KK (JP) 1996-09-25 EP disclosed
US-5407996-A Contacting with an aqueous solution of metal ion or metal oxide to form a gel; calcining SHOWA DENKO K.K. (JP) 1995-04-18 US disclosed
US-5338815-A Used in thickeners, dispersion stabilizers and lubricants SHOWA DENKO K.K. (JP) 1994-08-16 US disclosed
US-5300606-A Crosslinked N-vinylamide resin SHOWA DENKO K.K. (JP) 1994-04-05 US disclosed
US-5280095-A N-vinylcarboxylic acid amine resin SHOWA DENKO K.K. (JP) 1994-01-18 US disclosed
EP-0510246-A1 Use of fine particulate crosslinked type n-vinylamide resin microgel SHOWA DENKO KABUSHIKI KAISHA (JP) 1992-10-28 EP disclosed
EP-0473881-A1 Liquid absorption agent SHOWA DENKO KABUSHIKI KAISHA (JP) 1992-03-11 EP disclosed