SCHEMBL7929809

SCHEMBL7929809

C=CNC(=O)Cc1ccc(CC(=O)NC=C)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
CNR2 P34972 1/20 0.43
HTT P42858 2/20 0.42
GAA P10253 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
ALDH1A1 P00352 2/20 0.42
EGFR P00533 1/20 0.42
ERBB2 P04626 1/20 0.42
EPHX2 P34913 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
POLB P06746 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KCNH2 Q12809 1/20 0.41
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10284708 0.90 GAA (0.58) LMNAKMT2AHTTGAASMN1; SMN2
SCHEMBL2136285 0.90 MEN1 (0.59) LMNAMEN1KMT2AHDAC8HDAC6
SCHEMBL7938746 0.84 MEN1 (0.42) MEN1KMT2AHDAC8HDAC6GAA
SCHEMBL21566634 0.83 KDM4E (0.55) LMNAGAAALDH1A1POLBHPGD
SCHEMBL7929822 0.78 HDAC1 (0.50) HDAC8HDAC6HTTGAAALDH1A1
SCHEMBL98393 0.72 HTT (0.43) LMNAMEN1KMT2AHDAC8HDAC6
SCHEMBL4680710 0.72 MEN1 (0.59) LMNAMEN1KMT2AHDAC8HDAC6
SCHEMBL22338362 0.70 RAB9A (0.50) MEN1KMT2ASMN1; SMN2ALDH1A1NPC1
SCHEMBL11153839 0.70 MEN1 (0.55) MEN1KMT2AHDAC8HDAC6CNR2
SCHEMBL4111953 0.70 AOC2 (0.51) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0473881-B1 Liquid absorption agent SHOWA DENKO KK (JP) 2001-11-07 EP disclosed
US-5788950-A Method for the synthesis of mixed metal oxide powders SHOWA DENKO K.K. (JP) 1998-08-04 US disclosed
US-5744118-A MIXING ABSORBENT RESIN AND METAL SALTS, SWELLING AND GELATION, ADJUSTMENT OF PH, PYROLYSIS AND ROASTING SHOWA DENKO K.K. (JP) 1998-04-28 US disclosed
EP-0510246-B1 Use of fine particulate crosslinked type n-vinylamide resin microgel SHOWA DENKO KK (JP) 1996-09-25 EP disclosed
US-5407996-A Contacting with an aqueous solution of metal ion or metal oxide to form a gel; calcining SHOWA DENKO K.K. (JP) 1995-04-18 US disclosed
US-5338815-A Used in thickeners, dispersion stabilizers and lubricants SHOWA DENKO K.K. (JP) 1994-08-16 US disclosed
US-5300606-A Crosslinked N-vinylamide resin SHOWA DENKO K.K. (JP) 1994-04-05 US disclosed
US-5280095-A N-vinylcarboxylic acid amine resin SHOWA DENKO K.K. (JP) 1994-01-18 US disclosed
EP-0510246-A1 Use of fine particulate crosslinked type n-vinylamide resin microgel SHOWA DENKO KABUSHIKI KAISHA (JP) 1992-10-28 EP disclosed
EP-0473881-A1 Liquid absorption agent SHOWA DENKO KABUSHIKI KAISHA (JP) 1992-03-11 EP disclosed