Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4569224 | 0.83 | MAP4K4 (0.39) | MAP4K4 | |
| SCHEMBL19185470 | 0.75 | NR1I2 (0.31) | — | |
| SCHEMBL12462959 | 0.73 | TGFBR1 (0.32) | MAP4K4 | |
| SCHEMBL24983626 | 0.71 | SRC (0.40) | — | |
| SCHEMBL22607382 | 0.69 | CDK4 (0.36) | MAP4K4 | |
| SCHEMBL24983717 | 0.68 | LMNA (0.32) | — | |
| SCHEMBL400091 | 0.66 | MAP4K4 (0.55) | MAP4K4 | |
| SCHEMBL179556 | 0.66 | MAP4K4 (0.34) | MAP4K4 | |
| SCHEMBL179557 | 0.66 | MAP4K4 (0.34) | MAP4K4 | |
| SCHEMBL25468796 | 0.66 | MAP4K4 (0.32) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190282703-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE (ENPP) CONJUGATES AND USES THEREOF | ABBVIE INC. | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190282703-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE (ENPP) CONJUGATES AND USES THEREOF | ENPP1, ENPP3, ENPEP | MAP4K4 2955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.