Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21363952 | 0.87 | TGFBR1 (0.50) | TGFBR1CYP1A2CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL21363956 | 0.85 | GRM5 (0.40) | TGFBR1CYP1A2ALDH1A1MAPK10NPC1 | |
| SCHEMBL21364094 | 0.83 | TGFBR1 (0.40) | TGFBR1CYP1A2CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL15743711 | 0.83 | TGFBR1 (0.56) | TGFBR1CYP1A2CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL21364027 | 0.81 | GRM5 (0.43) | TGFBR1CYP1A2ALDH1A1MAPK10NPC1 | |
| SCHEMBL16526824 | 0.81 | TGFBR1 (0.66) | TGFBR1CYP1A2CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL16526825 | 0.81 | TGFBR1 (0.55) | TGFBR1CYP1A2CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL16526738 | 0.81 | TGFBR1 (0.58) | TGFBR1CYP1A2CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL16526669 | 0.80 | TGFBR1 (0.53) | TGFBR1CYP1A2CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL18643923 | 0.80 | TGFBR1 (0.53) | TGFBR1CYP1A2CYP2C19CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11145821-B2 | Organic electroluminescence device and polycyclic compound for organic electroluminescence device | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-10-12 | — | — | US | disclosed |
| US-20190288216-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11145821-B2 | Organic electroluminescence device and polycyclic compound for organic electroluminescence device | LEF1, SLC25A21, EMC2 | TGFBR1 2369/4885CYP1A2 317/4885CYP2C19 551/4885 |
| US-20190288216-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | LEF1, SLC25A21, EMC2 | TGFBR1 2369/4885CYP1A2 317/4885CYP2C19 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.