Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21364075 | 0.89 | TGFBR1 (0.45) | TGFBR1ALOX5APFEN1CYP1A2CYP2C19 | |
| SCHEMBL21364026 | 0.87 | TGFBR1 (0.53) | TGFBR1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL21364027 | 0.85 | GRM5 (0.43) | TGFBR1CYP1A2ALDH1A1GRM5MAPK10 | |
| SCHEMBL21364095 | 0.83 | BRD4 (0.42) | TGFBR1ALOX5APFEN1CYP1A2CYP2C19 | |
| SCHEMBL2189195 | 0.83 | TGFBR1 (0.52) | TGFBR1ALOX5APFEN1TSHRALDH1A1 | |
| SCHEMBL21363956 | 0.81 | GRM5 (0.40) | TGFBR1CYP1A2ALDH1A1GRM5MAPK10 | |
| SCHEMBL21364094 | 0.77 | TGFBR1 (0.40) | TGFBR1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL22426647 | 0.77 | PDK2 (0.47) | TGFBR1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL12345148 | 0.77 | ASIC3 (0.46) | TGFBR1CYP1A2CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL24104234 | 0.76 | BRD4 (0.50) | TGFBR1GRM5MAPK14LCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11145821-B2 | Organic electroluminescence device and polycyclic compound for organic electroluminescence device | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-10-12 | — | — | US | disclosed |
| US-20190288216-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11145821-B2 | Organic electroluminescence device and polycyclic compound for organic electroluminescence device | LEF1, SLC25A21, EMC2 | TGFBR1 2369/4885ALOX5AP 3935/4885FEN1 2358/4885 |
| US-20190288216-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | LEF1, SLC25A21, EMC2 | TGFBR1 2369/4885ALOX5AP 3935/4885FEN1 2358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.