SCHEMBL21364079

SCHEMBL21364079

CO[Si](C)(C=O)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 1/20 0.32
CA4 P22748 1/20 0.32
CYP2A6 P11509 1/20 0.32
TSHR P16473 1/20 0.31
ADH1B P00325 1/20 0.30
ADH1C P00326 1/20 0.30
ADH1A P07327 1/20 0.30
ADH7 P40394 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6550222 0.80 MAPT (0.36) MAPTESR1ESR2CA4
SCHEMBL296246 0.78 ESR1 (0.34) MAPTESR1ESR2ALDH1A1CA4
SCHEMBL29227821 0.77 ESR1 (0.33) MAPTESR1ESR2ALDH1A1CA4
SCHEMBL23921616 0.76 ALDH1A1 (0.34) MAPTESR1ESR2ALDH1A1KMT2A
SCHEMBL18638324 0.76 CA4 (0.39) MAPTESR1ESR2ALDH1A1KMT2A
SCHEMBL21082152 0.72 MAPT (0.39) MAPTESR1ESR2ALDH1A1KMT2A
SCHEMBL24348304 0.71
SCHEMBL704149 0.69 CA1 (0.41) MAPTESR1ESR2ALDH1A1CA4
SCHEMBL9466367 0.69 ESR1 (0.41) MAPTESR1ESR2ALDH1A1KMT2A
SCHEMBL48955 0.69 ESR1 (0.41) MAPTESR1ESR2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10781335-B2 Functional film DAIKIN INDUSTRIES, LTD. (JP) 2020-09-22 US disclosed
US-10731048-B2 2020-08-04 US disclosed
US-20190284431-A1 FUNCTIONAL FILM DAIKIN INDUSTRIES, LTD. (JP) 2019-09-19 US disclosed