SCHEMBL21082152

SCHEMBL21082152

C[Si](C=O)(C=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
ALDH1A1 P00352 6/20 0.39
CYP2A6 P11509 1/20 0.38
LMNA P02545 2/20 0.37
MAPK1 P28482 2/20 0.37
TRPA1 O75762 1/20 0.37
ALOX5 P09917 1/20 0.37
ADH1B P00325 1/20 0.34
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
ADH7 P40394 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
TAAR1 Q96RJ0 1/20 0.33
THRB P10828 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL160355 0.74 ESR1 (0.39) MAPTESR1ESR2ALDH1A1LMNA
SCHEMBL18638324 0.73 CA4 (0.39) MAPTESR1ESR2ALDH1A1CYP2A6
SCHEMBL20792266 0.72 ALDH1A1 (0.42) MAPTESR1ESR2ALDH1A1CYP2A6
SCHEMBL28545159 0.72 ALDH1A1 (0.42) MAPTESR1ESR2ALDH1A1CYP2A6
Formamide SCHEMBL28311018 0.72 MAPT (0.42) MAPTESR1ESR2ALDH1A1CYP2A6
SCHEMBL21364079 0.72 MAPT (0.35) MAPTESR1ESR2ALDH1A1CYP2A6
SCHEMBL28721082 0.72 ALDH1A1 (0.41) MAPTESR1ESR2ALDH1A1CYP2A6
SCHEMBL304128 0.70 MAPT (0.37) MAPTESR1ESR2ALDH1A1CYP2A6
SCHEMBL434194 0.69 ESR1 (0.44) MAPTESR1ESR2ALDH1A1LMNA
SCHEMBL28911 0.69 ESR1 (0.44) MAPTESR1ESR2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572434-B2 Curable composition, method for producing same, and article using same DAIKIN INDUSTRIES, LTD. (JP) 2023-02-07 US disclosed
US-20210189052-A1 CURABLE COMPOSITION, METHOD FOR PRODUCING SAME, AND ARTICLE USING SAME DAIKIN INDUSTRIES, LTD. (JP) 2021-06-24 US disclosed
US-20190169445-A1 SURFACE-TREATING AGENT AND ARTICLE COMPRISING LAYER FORMED FROM SURFACE-TREATING AGENT DAIKIN INDUSTRIES, LTD. (JP) 2019-06-06 US disclosed