Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14296207 | 0.89 | KMT2A (0.39) | KMT2AMEN1SMN1; SMN2KDM4EHTT | |
| SCHEMBL20991257 | 0.85 | RIPK1 (0.41) | KMT2AMEN1SMN1; SMN2KDM4EHTT | |
| SCHEMBL16202457 | 0.85 | KMT2A (0.39) | KMT2AMEN1SMN1; SMN2KDM4EHTT | |
| SCHEMBL18179935 | 0.84 | KMT2A (0.40) | KMT2AMEN1SMN1; SMN2KDM4EHTT | |
| SCHEMBL25890671 | 0.82 | KMT2A (0.37) | KMT2AMEN1SMN1; SMN2KDM4EHTT | |
| SCHEMBL21366311 | 0.82 | KMT2A (0.39) | KMT2AMEN1SMN1; SMN2KDM4EHTT | |
| SCHEMBL21089788 | 0.82 | SMN1; SMN2 (0.34) | KMT2AMEN1SMN1; SMN2KDM4EHTT | |
| SCHEMBL20215068 | 0.81 | RIPK1 (0.38) | KMT2AMEN1SMN1; SMN2KDM4EHTT | |
| SCHEMBL22472682 | 0.81 | KDM4E (0.47) | SMN1; SMN2KDM4EHTTNPSR1HSD17B3 | |
| SCHEMBL19687876 | 0.81 | KMT2A (0.34) | KMT2AMEN1SMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662215-B2 | Cyclic peroxides as prodrugs for selective delivery of agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-05-26 | — | — | US | disclosed |
| US-20190284224-A1 | CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662215-B2 | Cyclic peroxides as prodrugs for selective delivery of agents | GPX4, PRDX1, PRDX3 | KMT2A 3813/4885MEN1 4056/4885SMN1; SMN2 991/4885 |
| US-20190284224-A1 | CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS | GPX4, PRDX1, PRDX3 | KMT2A 3813/4885MEN1 4056/4885SMN1; SMN2 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.