SCHEMBL25890671

SCHEMBL25890671

CC(C)(C)Cn1nnc2c1-c1ccccc1N(C(=O)C(C)(C)C)Cc1ccccc1-2

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
RIPK1 Q13546 3/20 0.34
HSD17B3 P37058 2/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
KDM4E B2RXH2 1/20 0.34
HTT P42858 1/20 0.34
NOTUM Q6P988 1/20 0.33
IDO1 P14902 5/20 0.32
TDO2 P48775 5/20 0.32
ALDH1A1 P00352 1/20 0.31
DUSP10 Q9Y6W6 1/20 0.31
POLB P06746 1/20 0.30
IDH1 O75874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25890666 0.96 KMT2A (0.37) KMT2AMEN1RIPK1HSD17B3SMN1; SMN2
SCHEMBL25891385 0.88 TDO2 (0.35) HSD17B3SMN1; SMN2KDM4EHTTNOTUM
SCHEMBL18179935 0.87 KMT2A (0.40) KMT2AMEN1RIPK1HSD17B3SMN1; SMN2
SCHEMBL14296207 0.84 KMT2A (0.39) KMT2AMEN1RIPK1HSD17B3SMN1; SMN2
SCHEMBL21366311 0.83 KMT2A (0.39) KMT2AMEN1RIPK1HSD17B3SMN1; SMN2
SCHEMBL21366027 0.82 KMT2A (0.36) KMT2AMEN1RIPK1HSD17B3SMN1; SMN2
SCHEMBL25892503 0.81 SMN1; SMN2 (0.31) SMN1; SMN2KDM4EHTTPOLB
SCHEMBL24479357 0.81 IDO1 (0.30) IDO1TDO2
SCHEMBL19687876 0.80 KMT2A (0.34) KMT2AMEN1RIPK1HSD17B3SMN1; SMN2
SCHEMBL16202457 0.79 KMT2A (0.39) KMT2AMEN1RIPK1HSD17B3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235082-A1 SITE-SPECIFIC ANTIBODY CONJUGATES AND THE METHODS FOR PREPARATION OF THE SAME GLYCO-THERAPY BIOTECHNOLOGY CO., LTD. (CN) 2023-07-27 US disclosed
US-20230235082-A1 SITE-SPECIFIC ANTIBODY CONJUGATES AND THE METHODS FOR PREPARATION OF THE SAME GLYCO-THERAPY BIOTECHNOLOGY CO., LTD. (CN) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235082-A1 SITE-SPECIFIC ANTIBODY CONJUGATES AND THE METHODS FOR PREPARATION OF THE SAME FUT5, FUT6, SIGLEC7 KMT2A 2082/4885MEN1 2127/4885RIPK1 1876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.