Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21368468 | 1.00 | CRHBP (0.34) | CRHBPCRHR2KEAP1NFE2L2PDK2 | |
| SCHEMBL23546655 | 1.00 | CRHBP (0.34) | CRHBPCRHR2KEAP1NFE2L2PDK2 | |
| SCHEMBL21368473 | 0.98 | PDK2 (0.34) | CRHBPCRHR2KEAP1NFE2L2PDK2 | |
| SCHEMBL24029499 | 0.94 | CRHBP (0.33) | CRHBPCRHR2KEAP1NFE2L2PDK2 | |
| SCHEMBL21886350 | 0.94 | MEN1 (0.36) | CRHBPCRHR2KEAP1NFE2L2PDK2 | |
| SCHEMBL23546668 | 0.93 | CRHBP (0.33) | CRHBPCRHR2KEAP1NFE2L2PDK2 | |
| SCHEMBL21368472 | 0.92 | PDK2 (0.33) | CRHBPCRHR2KEAP1NFE2L2PDK2 | |
| SCHEMBL21886348 | 0.92 | MEN1 (0.31) | PDK2MEN1KMT2AUSP2MAPT | |
| SCHEMBL19829571 | 0.91 | PDK2 (0.37) | PDK2MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL24254028 | 0.91 | MEN1 (0.30) | PDK2MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11302870-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2022-04-12 | — | — | US | disclosed |
| US-20190288206-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11302870-B2 | Materials for electronic devices | EFNA1, PNMT, FLNB | CRHBP 4223/4885CRHR2 4467/4885KEAP1 751/4885 |
| US-20190288206-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, PNMT, FLNB | CRHBP 4218/4885CRHR2 4480/4885KEAP1 737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.