SCHEMBL21886348

SCHEMBL21886348

CC1(C)c2ccccc2-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc4c5c(cccc35)-c3ccccc3C(c3ccccc3)(c3ccccc3)c3ccccc3-4)cc21

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
USP2 O75604 1/20 0.31
PDK2 Q15119 2/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
OPRK1 P41145 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21368173 0.95 PDK2 (0.31) PDK2
SCHEMBL21368295 0.92 PDK2 (0.32) MEN1KMT2AUSP2PDK2KDM4E
SCHEMBL23546655 0.92 CRHBP (0.34) MEN1KMT2AUSP2PDK2KDM4E
SCHEMBL21368066 0.92 CRHBP (0.34) MEN1KMT2AUSP2PDK2KDM4E
SCHEMBL21368468 0.92 CRHBP (0.34) MEN1KMT2AUSP2PDK2KDM4E
SCHEMBL21368473 0.90 PDK2 (0.34) MEN1KMT2AUSP2PDK2LMNA
SCHEMBL21886350 0.89 MEN1 (0.36) MEN1KMT2AUSP2PDK2KDM4E
SCHEMBL21368180 0.88 PDK2 (0.34) MEN1KMT2AUSP2PDK2LMNA
SCHEMBL23349259 0.88 PDK2 (0.32) PDK2
SCHEMBL24029499 0.87 CRHBP (0.33) MEN1KMT2AUSP2PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220052272-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-02-17 US disclosed
WO-2020055113-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2020-03-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220052272-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TMEM109, OR10J3, LEF1 MEN1 1166/4885KMT2A 2426/4885USP2 4635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.