Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.53 |
| ▸ | TTR | P02766 | 3/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21370549 | 0.90 | CYP1A1 (0.52) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL21370547 | 0.89 | CYP1A1 (0.60) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL21370604 | 0.80 | TTR (0.70) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL21370626 | 0.79 | KMT2A (0.52) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL21370551 | 0.78 | PTGS2 (0.53) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL21356573 | 0.78 | PTGS2 (0.53) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL21356574 | 0.78 | PTGS2 (0.53) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL21370554 | 0.76 | KMT2A (0.50) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL2517590 | 0.76 | ESR1 (0.68) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL2517589 | 0.76 | ESR1 (0.68) | PTGS2CYP1A1CYP1B1TTRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365208-B2 | Silylated derivatives of resveratrol and the use thereof in neurodegenerative, neurological or inflammatory diseases | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2022-06-21 | — | — | US | disclosed |
| US-20190284213-A1 | SILYLATED DERIVATIVES OF RESERVATROL AND THE USE THEREOF IN NEURODEGENERATIVE, NEUROLOGICAL OR INFLAMMATORY DISEASES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365208-B2 | Silylated derivatives of resveratrol and the use thereof in neurodegenerative, neurological or inflammatory diseases | SNCA, SIRT1, SIRT5 | PTGS2 1007/4885CYP1A1 2689/4885CYP1B1 3037/4885 |
| US-20190284213-A1 | SILYLATED DERIVATIVES OF RESERVATROL AND THE USE THEREOF IN NEURODEGENERATIVE, NEUROLOGICAL OR INFLAMMATORY DISEASES | SIRT1, SIRT3, SIRT2 | PTGS2 1476/4885CYP1A1 2022/4885CYP1B1 2129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.