SCHEMBL2137121

SCHEMBL2137121

Brc1ccc2c(c1)Cc1cc(I)ccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 1/20 0.47
TDP2 O95551 3/20 0.46
PGR P06401 2/20 0.42
SRD5A1 P18405 1/20 0.41
SRD5A2 P31213 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CHEK2 O96017 1/20 0.40
ROS1 P08922 1/20 0.40
MARK3 P27448 1/20 0.40
LTK P29376 1/20 0.40
FLT4 P35916 1/20 0.40
KDR P35968 1/20 0.40
MINK1 Q8N4C8 1/20 0.40
AURKB Q96GD4 1/20 0.40
PBK Q96KB5 1/20 0.40
STK17A Q9UEE5 1/20 0.40
MAP4K5 Q9Y4K4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL783976 0.88 SRD5A1 (0.53) METAP1TDP2SRD5A1SRD5A2PARP10
SCHEMBL481427 0.87 TDP2 (0.55) TDP2SRD5A2PNMTADRA2AADRA2B
SCHEMBL40823 0.87 METAP1 (0.57) METAP1TDP2PGRSRD5A1SRD5A2
SCHEMBL28126153 0.87 METAP1 (0.57) METAP1TDP2PGRSRD5A1SRD5A2
Ammonia Solution, Strong SCHEMBL28144371 0.84 METAP1 (0.55) METAP1TDP2PGRSRD5A1SRD5A2
SCHEMBL27619851 0.84 METAP1 (0.55) METAP1TDP2PGRSRD5A1SRD5A2
SCHEMBL4826135 0.82 METAP1 (0.53) METAP1TDP2PGRSRD5A1SRD5A2
SCHEMBL3129344 0.80 METAP1 (0.52) METAP1TDP2PGRSRD5A1SRD5A2
SCHEMBL19417357 0.79 METAP1 (0.43) METAP1TDP2PGRSRD5A1SRD5A2
SCHEMBL4912147 0.77 METAP1 (0.48) METAP1TDP2PGRSRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100489006-C Method for preparing poly (9,9 dialkyl fluorene) CHANGCHUN APPLIED CHEMISTRY (CN) 2009-05-20 CN claimed
CN-101092475-A Method for preparing poly (9,9 di alkyl fluorene) CHANGCHUN APPLIED CHEMISTRY (CN) 2007-12-26 CN claimed
EP-4465801-A1 IRIDIUM COMPLEX COMPOUND, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR PRODUCING SAME, AND DISPLAY DEVICE Mitsubishi Chemical Corporation (JP) 2024-11-20 EP disclosed
US-20240373739-A1 IRIDIUM COMPLEX COMPOUND, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, METHOD FOR PRODUCING SAME, AND DISPLAY DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2024-11-07 US disclosed
US-12133453-B2 Polymer, composition for organic electroluminescent element, organic electroluminescent element, organic EL display device, organic EL lighting, and manufacturing method for organic electroluminescent element MITSUBISHI CHEMICAL CORPORATION (JP) 2024-10-29 US disclosed
CN-116496493-B Polymer, composition for organic EL element, and method for producing same 三菱化学株式会社 2024-09-06 CN disclosed
CN-117903077-B Dihydrooxadiazinone compound and application thereof 上海超阳药业有限公司 2024-09-03 CN disclosed
CN-118556453-A Iridium complex, composition for organic electroluminescent element, method for producing organic electroluminescent element, and display device 三菱化学株式会社 2024-08-27 CN disclosed
CN-117903077-A Dihydrooxadiazinon compound and application thereof 上海超阳药业有限公司 2024-04-19 CN disclosed
US-20240107870-A1 POLYMER, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY DEVICE, ORGANIC EL LIGHTING, AND MANUFACTURING METHOD FOR ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2024-03-28 US disclosed
CN-117757066-A Polymer, composition for organic EL element, and method for producing same 三菱化学株式会社 2024-03-26 CN disclosed
US-7199167-B2 Light emitting polymer UNIVERSITY OF HULL (GB) 2007-04-03 US disclosed
US-7126013-B2 Mono-, oligo- and polymers comprising fluorene and aryl groups MERCK PATENT GMBH (DE) 2006-10-24 US disclosed
US-20060232198-A1 Aromatic triamine compound and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2006-10-19 US disclosed
US-20050096404-A1 Light emitting polymer UNIVERSITY OF HULL (GB) 2005-05-05 US disclosed
EP-1475401-A2 Mono-, oligo- and polymers comprising fluorene and aryl groups MERCK PATENT GmbH (DE) 2004-11-10 EP disclosed
US-20040176560-A1 Mono-, Oligo-and polymers comprising fluorene and aryl groups MERCK PATENT GMBH (DE) 2004-09-09 US disclosed
US-6730793-B1 FUSED THIAZOLE DERIVATIVES; MICROELECTROMECHANICAL SYSTEMS, PHOTODYNAMIC THERAPY THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2004-05-04 US disclosed
US-6555682-B1 S-triazines substituted by 1,3,5-tri(7-benzothiazol-2-yl or 7-diphenylamino fluoren-2-yl dericatives; absorption cross-sections; lasers; fluorescent dyes THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2003-04-29 US disclosed
JP-2001010996-A FLUORENE COMPOUND MITSUI CHEMICALS INC 2001-01-16 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060232198-A1 Aromatic triamine compound and organic electroluminescence device using the same TYR, PNMT, ALK METAP1 2159/4885TDP2 841/4885PGR 2284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.