Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 5/20 | 0.52 |
| ▸ | CTSS | P25774 | 5/20 | 0.52 |
| ▸ | CTSB | P07858 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.50 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12142665 | 1.00 | SYK (0.53) | SYKCTRB1ATMELANECTSL | |
| SCHEMBL14569563 | 0.88 | CTRB1 (0.59) | SYKCTRB1ATMELANECTSL | |
| SCHEMBL13036482 | 0.88 | CTRB1 (0.59) | SYKCTRB1ATMELANECTSL | |
| SCHEMBL13219608 | 0.88 | SYK (0.60) | SYKCTRB1ATMELANECTSL | |
| SCHEMBL12564718 | 0.88 | SYK (0.60) | SYKCTRB1ATMELANECTSL | |
| SCHEMBL14569560 | 0.87 | CTSK (0.62) | SYKATMELANECTSLCTSS | |
| SCHEMBL6963239 | 0.87 | CASP1 (0.53) | SYKCTRB1ATMELANECTSL | |
| SCHEMBL13036484 | 0.87 | CTSK (0.62) | SYKATMELANECTSLCTSS | |
| SCHEMBL7389166 | 0.86 | SYK (0.51) | SYKCTRB1ATMELANECTSL | |
| SCHEMBL8035611 | 0.86 | SYK (0.54) | SYKCTRB1ATMELANECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4596051-A2 | HSPC-SPARING TREATMENTS FOR RB-POSITIVE ABNORMAL CELLULAR PROLIFERATION | Pharmacosmos Holding A/s (DK) | 2025-08-06 | — | — | EP | disclosed |
| EP-2968291-B1 | HSPC-SPARING TREATMENTS FOR RB-POSITIVE ABNORMAL CELLULAR PROLIFERATION | PHARMACOSMOS HOLDING AS (DK) | 2025-04-16 | — | — | EP | disclosed |
| EP-3653209-A1 | TRANSIENT PROTECTION OF NORMAL CELLS DURING CHEMOTHERAPY | G1 Therapeutics, Inc. (US) | 2020-05-20 | — | — | EP | disclosed |
| EP-2968290-B1 | TRANSIENT PROTECTION OF NORMAL CELLS DURING CHEMOTHERAPY | G1 THERAPEUTICS INC (US) | 2019-09-25 | — | — | EP | disclosed |
| CN-106008533-B | CDK inhibitor | G1治疗公司 | 2018-01-23 | — | — | CN | disclosed |
| CN-106967074-A | CDK inhibitor | G1治疗公司 | 2017-07-21 | — | — | CN | disclosed |
| CN-103936745-B | Cdk inhibitors | G1治疗公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-106008533-A | Cdk inhibitors | G1治疗公司 | 2016-10-12 | — | — | CN | disclosed |