Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | C1R | P00736 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27547396 | 0.88 | RAB9A (0.49) | NPC1ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL27520950 | 0.85 | ALDH1A1 (0.64) | NPC1ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL7304362 | 0.82 | DHODH (0.56) | DHODHNPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30594910 | 0.80 | DHODH (0.54) | DHODHNPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31570210 | 0.79 | ELANE (0.65) | NPC1ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL13865472 | 0.79 | ESR2 (0.82) | ALDH1A1KDM4EESR1ESR2HPGD | |
| SCHEMBL6655585 | 0.79 | ELANE (0.65) | NPC1ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL29138308 | 0.79 | C1R (0.53) | DHODHNPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2587399 | 0.78 | DHODH (0.58) | DHODHNPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20413954 | 0.78 | JAK2 (0.48) | DHODHNPC1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242278-B2 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20120101278-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | HAGIYA KOJI (JP) | 2012-04-26 | — | — | US | disclosed |
| EP-1473286-B1 | PROCESS FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | HAGIYA KOJI | 2009-08-27 | — | — | US | disclosed |
| US-7554000-B2 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |
| CN-1293042-C | Aromatic amino acid derivative and pharmaceutical composition thereof | HITOSHI ENDOU (JP) | 2007-01-03 | — | — | CN | disclosed |
| CN-1630632-A | Aromatic amino acid derivative and pharmaceutical composition thereof | HITOSHI ENDOU (JP) | 2005-06-22 | — | — | CN | disclosed |
| US-20050096471-A1 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |
| EP-1473286-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2004-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101278-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | PPOX, CAT, TYR | DHODH 657/4885NPC1 4102/4885ALDH1A1 1191/4885 |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | PPOX, CAT, TYR | DHODH 657/4885NPC1 4102/4885ALDH1A1 1191/4885 |
| US-20050096471-A1 | Process for producing biaryl compound | PPOX, CAT, TYR | DHODH 657/4885NPC1 4102/4885ALDH1A1 1191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.