Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17229936 | 0.97 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14280528 | 0.97 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL676406 | 0.96 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL26363956 | 0.93 | TSHR (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17229939 | 0.93 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17229941 | 0.91 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14571766 | 0.90 | TSHR (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17229940 | 0.88 | THRB (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2367984 | 0.85 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5446210 | 0.85 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773289-B2 | Organofunctional siloxanes, process for preparing same and their use for the treatment of fillings and surfaces | ABCR LABORATORIOS, S.L. (ES) | 2023-10-03 | — | — | US | disclosed |
| US-20200332149-A1 | ORGANOFUNCTIONAL SILOXANES, PROCESS FOR PREPARING SAME AND THEIR USE FOR THE TREATMENT OF FILLINGS AND SURFACES | ABCR LABORATORIOS, S.L. (ES) | 2020-10-22 | — | — | US | disclosed |
| EP-3543304-B1 | ORGANOFUNCTIONAL SILOXANES, METHOD FOR ITS PREPARATION AND USE FOR THE TREATMENT OF FILLERS AND SURFACES | ABCR LABORATORIOS S L (ES) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019180285-A2 | ORGANOFUNCTIONAL SILOXANES, PROCESS FOR PREPARING SAME AND THEIR USE FOR THE TREATMENT OF FILLINGS AND SURFACES | ABCR LABORATORIOS, S.L. (ES) | 2019-09-26 | — | — | WO | disclosed |
| EP-3543304-A1 | ORGANOFUNCTIONAL SILOXANES, METHOD FOR ITS PREPARATION AND USE FOR THE TREATMENT OF FILLERS AND SURFACES | ABCR Laboratorios, S.L. (ES) | 2019-09-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200332149-A1 | ORGANOFUNCTIONAL SILOXANES, PROCESS FOR PREPARING SAME AND THEIR USE FOR THE TREATMENT OF FILLINGS AND SURFACES | FDFT1, DBF4, IPO4 | TSHR 4675/4885THRB 4559/4885POLB 1792/4885 |
| US-11773289-B2 | Organofunctional siloxanes, process for preparing same and their use for the treatment of fillings and surfaces | FDFT1, DBF4, IPO4 | TSHR 4675/4885THRB 4559/4885POLB 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.