Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376803 | 0.82 | RXFP1 (0.56) | L3MBTL1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL21910111 | 0.81 | CASP3 (0.45) | L3MBTL1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL21376787 | 0.79 | AKR1C3 (0.53) | RAB9ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL21376581 | 0.77 | ADORA3 (0.57) | L3MBTL1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL665055 | 0.76 | L3MBTL1 (1.00) | L3MBTL1RAB9ANR2F2SMN1; SMN2ALDH1A1 | |
| SCHEMBL21376808 | 0.75 | RAB9A (0.54) | RAB9ASMN1; SMN2ALDH1A1TP53MAPT | |
| SCHEMBL21909808 | 0.75 | MAPT (0.58) | RAB9ASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL21376790 | 0.75 | MEN1 (0.38) | L3MBTL1SMN1; SMN2ALDH1A1TP53MAPT | |
| SCHEMBL21376788 | 0.73 | AKR1C3 (0.54) | SMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL7096462 | 0.71 | NT5E (0.68) | L3MBTL1RAB9ASMN1; SMN2NT5EJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |