Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 4/20 | 0.41 |
| ▸ | NOS2 | P35228 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320568 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP3A4HCAR2 | |
| SCHEMBL27664520 | 0.73 | ALDH1A1 (0.61) | ENPP2NOS1NOS2ALDH1A1NOS3 | |
| Hydrochloric Acid SCHEMBL27563549 | 0.72 | ALDH1A1 (0.59) | ENPP2NOS1NOS2ALDH1A1NOS3 | |
| SCHEMBL20109593 | 0.71 | ENPP2 (0.52) | ENPP2NOS1NOS2ALDH1A1NOS3 | |
| SCHEMBL14704489 | 0.71 | LOXL2 (0.53) | ENPP2NOS1NOS2ALDH1A1NOS3 | |
| Iodide SCHEMBL29198612 | 0.71 | LOXL2 (0.67) | ENPP2NOS1NOS2ALDH1A1NOS3 | |
| SCHEMBL23395085 | 0.70 | CYP19A1 (0.39) | ALDH1A1CYP3A4LOXL2 | |
| SCHEMBL29011017 | 0.70 | ENPP2 (0.50) | ENPP2NOS1NOS2ALDH1A1NOS3 | |
| SCHEMBL2901465 | 0.70 | ENPP2 (0.54) | ENPP2NOS1NOS2ALDH1A1NOS3 | |
| SCHEMBL28325729 | 0.70 | ENPP2 (0.46) | ENPP2NOS1NOS2ALDH1A1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3101015-B1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME | EA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |