SCHEMBL21377909

SCHEMBL21377909

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1cc(-c2cccc(-n3c4ccncc4c4cnccc43)c2)cc(-n2c3ccc(C)cc3c3cc(C)ccc32)c1C#N

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.39
ACHE P22303 2/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
ALDH1A1 P00352 2/20 0.35
CYP11B2 P19099 2/20 0.34
PIP4K2A P48426 1/20 0.34
CYP11B1 P15538 1/20 0.34
MAOA P21397 1/20 0.34
KDM4E B2RXH2 1/20 0.32
MAP2K4 P45985 1/20 0.32
PIK3CD O00329 1/20 0.31
PDE10A Q9Y233 1/20 0.31
KMT2A Q03164 1/20 0.31
BTK Q06187 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21396894 0.96 CYP11B2 (0.39) ELANEACHEGRIN1GRIN2AALDH1A1
SCHEMBL21378046 0.90 CYP11B2 (0.39) ELANEACHEGRIN1GRIN2AALDH1A1
SCHEMBL21396825 0.85 CYP11B2 (0.38) ACHECYP11B2MAOAKDM4EPDE10A
SCHEMBL21396826 0.85 CYP11B2 (0.38) ELANEACHEGRIN1GRIN2AALDH1A1
SCHEMBL23912078 0.84 CYP11B2 (0.46) ALDH1A1CYP11B2CYP11B1MAOAKDM4E
SCHEMBL21377927 0.84 CYP11B2 (0.38) ACHECYP11B2CYP11B1MAOA
SCHEMBL21377939 0.84 CYP11B2 (0.38) ACHECYP11B2CYP11B1MAOA
SCHEMBL21378078 0.83 CYP11B2 (0.38) ELANEACHEGRIN1GRIN2AALDH1A1
SCHEMBL21377994 0.82 ACHE (0.40) ELANEACHEGRIN1GRIN2ACYP11B2
SCHEMBL21377979 0.82 ACHE (0.40) ELANEACHEGRIN1GRIN2ACYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11608333-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-03-21 US disclosed
US-20190292181-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES Kyulux North America, Inc. 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190292181-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, SLCO1B3, NDUFV3 ELANE 1300/4885ACHE 251/4885GRIN1 1201/4885
US-11608333-B2 Composition of matter for use in organic light-emitting diodes CRY2, SLCO1B3, NDUFV3 ELANE 1300/4885ACHE 251/4885GRIN1 1201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.