Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | F12 | P00748 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NT5C2 | P49902 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2514195 | 0.82 | BRD4 (0.47) | BRD4STAT3ADORA1PDPK1ADORA3 | |
| SCHEMBL23123 | 0.80 | BRD4 (0.64) | BRD4PDPK1NT5C2NT5EHTT | |
| SCHEMBL8121393 | 0.80 | STAT3 (0.69) | BRD4STAT3ADORA1ADORA3F2 | |
| SCHEMBL8381773 | 0.79 | BRD4 (0.63) | BRD4PDPK1NT5C2NT5EHTT | |
| SCHEMBL21356264 | 0.79 | RAB9A (0.47) | BRD4STAT3ADORA1PDPK1F2 | |
| SCHEMBL7717445 | 0.78 | BRD4 (0.51) | BRD4PDPK1ADORA3NT5C2KMT2A | |
| SCHEMBL6463473 | 0.77 | BRD4 (0.60) | BRD4ADORA1PDPK1ADORA3ADORA2A | |
| SCHEMBL3889223 | 0.76 | BRD4 (0.42) | BRD4ADORA1PDPK1ADORA3ADORA2A | |
| SCHEMBL4405832 | 0.76 | CYP1A2 (0.50) | BRD4STAT3ADORA1ADORA3F2 | |
| SCHEMBL25921184 | 0.76 | GAA (0.56) | ADORA1ADORA3ADORA2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126098-A | Method for synthesizing 2-amino adenosine and product thereof | 江苏欣德瑞医药科技有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-118126098-A | Method for synthesizing 2-amino adenosine and product thereof | 江苏欣德瑞医药科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| EP-0707481-B1 | L-2',3'-DIDEOXY NUCLEOSIDE ANALOGS AS ANTI-HEPATITIS B (HBV) AND ANTI-HIV AGENTS | UNIV YALE (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5830881-A | L-2'3',dideoxy nucleoside analogs as anti-hepatitus B (HBV) agents | YALE UNIVERSITY (US) | 1998-11-03 | — | — | US | disclosed |
| US-5631239-A | VIRICIDES FOR HEPATITIS | YALE UNIVERSITY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5627160-A | L-2',3'-dideoxy nucleoside analogs as anti-hepatitis B (HBV) and anti-HIV agents | YALE UNIVERSITY (US) | 1997-05-06 | — | — | US | disclosed |
| US-5561120-A | LOW TOXICITY TO HOST CELLS | YALE UNIVERSITY (US) | 1996-10-01 | — | — | US | disclosed |
| EP-0707481-A4 | — | — | 1996-05-29 | — | — | EP | disclosed |
| EP-0707481-A1 | L-2',3'-DIDEOXY NUCLEOSIDE ANALOGS AS ANTI-HEPATITIS B (HBV) AND ANTI-HIV AGENTS | YALE UNIVERSITY (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1994027616-A1 | L-2',3'-DIDEOXY NUCLEOSIDE ANALOGS AS ANTI-HEPATITIS B (HBV) AND ANTI-HIV AGENTS | YALE UNIVERSITY (US) | 1994-12-08 | — | — | WO | disclosed |