SCHEMBL2138

SCHEMBL2138

CCN(CC)CCOc1cccc(OCCN(CC)CC)c1OCCN(CC)CC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.58
DRD2 P14416 1/20 0.57
DRD1 P21728 1/20 0.57
DRD3 P35462 1/20 0.57
LMNA P02545 2/20 0.53
CHRM2 P08172 2/20 0.53
TSHR P16473 2/20 0.53
CHRM1 P11229 1/20 0.53
ALOX15 P16050 1/20 0.53
ACHE P22303 1/20 0.53
KCNH2 Q12809 1/20 0.53
HIF1A Q16665 1/20 0.53
ALDH1A1 P00352 3/20 0.53
HTR1B P28222 2/20 0.53
HTR1D P28221 1/20 0.53
BIRC5 O15392 1/20 0.50
CYP1A2 P05177 1/20 0.47
LTA4H P09960 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL418082 0.95 KDM4E (0.54) KDM4EDRD2DRD1DRD3LMNA
Hexamethonium SCHEMBL7212262 0.86 CHRM2 (0.49) KDM4EDRD2DRD1DRD3LMNA
SCHEMBL9706154 0.86 DRD3 (0.67) KDM4EDRD2DRD1DRD3LMNA
SCHEMBL9596044 0.85 LMNA (0.54) KDM4EDRD2DRD1DRD3LMNA
SCHEMBL14365443 0.82 KDM4E (0.46) KDM4EDRD2DRD1DRD3LMNA
SCHEMBL11209770 0.80 ALDH1A1 (0.65) KDM4EDRD2DRD1LMNACHRM2
SCHEMBL3265285 0.80 CHRM2 (0.59) KDM4EDRD2DRD1DRD3LMNA
SCHEMBL3989063 0.80 KDM4E (0.41) KDM4EDRD2DRD1DRD3LMNA
Guaiactamine SCHEMBL25797 0.79 ALDH1A1 (0.78) KDM4EDRD2DRD1DRD3LMNA
SCHEMBL28428684 0.79 DRD3 (0.59) KDM4EDRD2DRD1DRD3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3689 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4154879-B1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NICOTINE WITHDRAWAL SYMPTOMS KOREA INST SCI & TECH (KR) 2025-09-10 EP claimed
EP-4178948-A2 FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF Universidade de Santiago de Compostela (ES) 2023-05-17 EP claimed
EP-4154879-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NICOTINE WITHDRAWAL SYMPTOMS Korea Institute of Science and Technology (KR) 2023-03-29 EP claimed
WO-2022250365-A1 PHARMACEUTICAL COMPOSITION CONTAINING GALAMINE TRIETHIODIDE AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MUSCLE DISEASES 건국대학교 글로컬산학협력단 2022-12-01 WO claimed
EP-1931320-B1 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL DOSAGE FORM COMPRISING THE SAME FLAMEL IRELAND LTD (IE) 2022-06-15 EP claimed
WO-2022023496-A2 FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2022-02-03 WO claimed
WO-2020154746-A1 SKELETAL MUSCLE TARGETING MOIETIES AND USES THEREOF MANTRA BIO, INC. (US) 2020-07-30 WO claimed
US-10716779-B2 Methods and compositions for treating foot or hand pain SANDERS JENNIFER L (US) 2020-07-21 US claimed
EP-2547311-B1 KIT AND METHOD FOR DETECTING POROUS DENTAL HYDROXY APATITE INCISIVE TECH PTY LTD (AU) 2020-05-27 EP claimed
CN-110302414-A A kind of medical scar repairs silicone gel dressing and preparation method 广西信业生物技术有限公司 2019-10-08 CN claimed
US-5816707-A Reversible chemical thermometer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-10-06 US claimed
US-5770222-A Therapeutic drug delivery systems IMARX PHARMACEUTICAL CORP. (US) 1998-06-23 US claimed
EP-0684463-A1 Temperature indicating device and composition for use therein PyMaH Corporation (US) 1995-11-29 EP claimed
US-5401100-A Axillary thermometer packaging PYMAH CORPORATION (US) 1995-03-28 US claimed
US-5094545-A Solid solution with nucleating agent and indicator dye PYMA CORPORATION (US) 1992-03-10 US claimed
US-4362645-A Temperature indicating compositions of matter AKZONA, INC. (US) 1982-12-07 US claimed
US-4345470-A All plastic disposable thermometer AKZONA INCORPORATED (US) 1982-08-24 US claimed
US-4299727-A Disposable reversible thermometer AKZONA INCORPORATED (US) 1981-11-10 US claimed
US-4232552-A THERMOCHROMISM, DISPOSABLE THERMOMETERS AKZONA INCORPORATED (US) 1980-11-11 US claimed
US-4141688-A THIAZINE, OXAZINE, OR AZINE DYE INDICATOR MILES LABORATORIES, INC. (US) 1979-02-27 US claimed