Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2138 | 0.86 | KDM4E (0.58) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL418082 | 0.82 | KDM4E (0.54) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL3265285 | 0.77 | CHRM2 (0.59) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL9706154 | 0.74 | DRD3 (0.67) | CHRM2LMNATSHRCHRM1KCNH2 | |
| SCHEMBL9596044 | 0.73 | LMNA (0.54) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL13963708 | 0.71 | ALDH1A1 (0.71) | CHRM2LMNATSHRACHEALDH1A1 | |
| SCHEMBL14365443 | 0.70 | KDM4E (0.46) | LMNAACHEALDH1A1KDM4EHTR1B | |
| SCHEMBL11209770 | 0.69 | ALDH1A1 (0.65) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL453505 | 0.69 | CHRM2 (0.56) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL456438 | 0.69 | CHRM2 (0.56) | CHRM2LMNATSHRCHRM1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272170-A1 | OCULAR GROWTH AND NICOTINIC ANTAGONISTS | Valley Forge Pharmaceuticals, Inc. (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001052832-A1 | OCULAR GROWTH AND NICOTINIC ANTAGONISTS | VALLEY FORGE PHARMACEUTICALS, INC. (US) | 2001-07-26 | — | — | WO | disclosed |