Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2138 | 0.85 | KDM4E (0.58) | LMNAALDH1A1KDM4EDRD2DRD1 | |
| SCHEMBL418082 | 0.84 | KDM4E (0.54) | LMNAALDH1A1KDM4EDRD2DRD1 | |
| SCHEMBL3989063 | 0.76 | KDM4E (0.41) | LMNAALDH1A1KDM4EDRD2DRD1 | |
| SCHEMBL11807946 | 0.75 | ALDH1A1 (0.74) | LMNAALDH1A1KDM4EDRD2DRD1 | |
| SCHEMBL11338177 | 0.74 | ALDH1A1 (0.76) | LMNAALDH1A1KDM4EDRD2DRD1 | |
| SCHEMBL2211304 | 0.73 | ALDH1A1 (0.63) | LMNAALDH1A1KDM4EDRD2DRD1 | |
| Hexamethonium SCHEMBL7212262 | 0.73 | CHRM2 (0.49) | LMNAALDH1A1KDM4EDRD2DRD1 | |
| SCHEMBL9706154 | 0.73 | DRD3 (0.67) | LMNAALDH1A1KDM4EDRD2DRD1 | |
| Hydrochloric Acid SCHEMBL11671640 | 0.72 | ALDH1A1 (0.74) | LMNAALDH1A1KDM4EDRD2DRD1 | |
| SCHEMBL8340067 | 0.70 | LMNA (0.70) | LMNAALDH1A1KDM4EDRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236922-A | Method for treating depression using 1-(aminophenyl)-2-aminopropanone derivatives | LABORATOIRE L. LAFON (FR) | 1993-08-17 | — | — | US | disclosed |
| US-4980377-A | ANTIDEPRESSANTS, VASODILATION, IMMUNOSTIMULANTS | LABORATOIRE L. LAFON (FR) | 1990-12-25 | — | — | US | disclosed |
| US-4963570-A | ANTIDEPRESSANTS; CENTRAL NERVOUS SYSTEM | LABORATOIRE L. LAFON (FR) | 1990-10-16 | — | — | US | disclosed |
| US-4933442-A | 1-(acetylaminophenyl)-2-aminopropanone derivatives and central nervous system antidepressant compositions | LABORATOIRE L. LAFON (FR) | 1990-06-12 | — | — | US | disclosed |
| US-4933370-A | ANTIDEPRESSANTS, IMMUNOSTIMULANTS | LABORATOIRE L. LAFON (FR) | 1990-06-12 | — | — | US | disclosed |
| US-4912110-A | Antidepressive substituted phenylpiperazine compounds | LABORATOIRE L. LAFTON (FR) | 1990-03-27 | — | — | US | disclosed |
| US-4877812-A | 1-(acetylaminophenyl)-2-aminopropanone derivatives and antidepressant compositions thereof | LABORATOIRE L. LAFON (FR) | 1989-10-31 | — | — | US | disclosed |
| US-4861801-A | Treatment of depression by using a fluorophenacylamine derivative | Lafon, Laboratoire L. (FR) | 1989-08-29 | — | — | US | disclosed |
| US-4847274-A | CENTRAL NERVOUS SYSTEM, SEDATIVES | LABORATOIRE L. LAFON (FR) | 1989-07-11 | — | — | US | disclosed |
| US-4835315-A | Fluorophenacyl-amine derivatives and application thereof in therapeutics | LABORATOIRE L. LAFON (FR) | 1989-05-30 | — | — | US | disclosed |
| US-4690950-A | ANTIDEPRESSANTS, STIMULANTS | LABORATOIRE L. LAFON (FR) | 1987-09-01 | — | — | US | disclosed |
| US-4663328-A | 3-Phenyl-tetrahydropyridine derivatives, and their use as sedative agents | LABORATOIRE L. LAFON (FR) | 1987-05-05 | — | — | US | disclosed |
| US-4603019-A | N-(methoxyphenacyl)-amine derivatives | LABORATOIRE L. LAFON (FR) | 1986-07-29 | — | — | US | disclosed |
| US-4576944-A | STIMULANTS, ANTIDEPRESSANTS | LABORATOIRE L. LAFON (FR) | 1986-03-18 | — | — | US | disclosed |
| US-4545996-A | ANTIDEPRESSANTS; PSYCHOSTIMULANTS; CENTRAL NERVOUS SYSTEM | LABORATOIRE L. LAFON (FR) | 1985-10-08 | — | — | US | disclosed |
| US-4489095-A | PSYCHOTONIC AND ANTIAGGRESSION AGENTS | LABORATOIRE L. LAFON (FR) | 1984-12-18 | — | — | US | disclosed |
| US-4407822-A | SEDATIVES | LABORATOIRE L. LAFON (FR) | 1983-10-04 | — | — | US | disclosed |
| US-4271194-A | Sedative compositions containing (3,4-dichlorophenylsulphinyl)-acetamidoxime and its addition salts and method of use | LABORATOIRE L. LAFON (FR) | 1981-06-02 | — | — | US | disclosed |
| US-4025649-A | INHIBITORS OF A TRANSAMINASE ENZYME, ANTIANOXIC, ANTICONVULSANT | LABAZ (FR) | 1977-05-24 | — | — | US | disclosed |
| US-3958011-A | ADMINISTERING | LABAZ (FR) | 1976-05-18 | — | — | US | disclosed |