Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4465330 | 0.88 | NPC1 (0.37) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL4464367 | 0.79 | PNMT (0.33) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL29573677 | 0.73 | PNMT (0.38) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL820366 | 0.73 | PNMT (0.36) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL714922 | 0.70 | NPC1 (0.49) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL2168145 | 0.70 | PNMT (0.33) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL820095 | 0.70 | PNMT (0.33) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL715903 | 0.68 | NPC1 (0.38) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL820385 | 0.68 | PNMT (0.32) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL715314 | 0.67 | NPC1 (0.39) | PNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9416069-B2 | Scalable production of precision hydrocarbons from trialkylaluminum via ternary living coordinative chain transfer polymerization | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2016-08-16 | — | — | US | disclosed |
| US-9175103-B2 | Living coordinative chain transfer polymerization with dynamic counterion exchange | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2015-11-03 | — | — | US | disclosed |
| EP-2220128-B1 | PROCESS FOR PREPARATION OF POLYOLEFINS VIA LIVING COORDINATIVE CHAIN TRANSFER POLYMERIZATION | UNIV MARYLAND (US) | 2014-10-22 | — | — | EP | disclosed |
| US-20140073752-A1 | Living Coordinative Chain Transfer Polymerization with Dynamic Counterion Exchange | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2014-03-13 | — | — | US | disclosed |
| US-20130109900-A1 | Scalable Production of Precision Hydrocarbons from Trialkylaluminum via Ternary Living Coordinative Chain Transfer Polymerization | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2013-05-02 | — | — | US | disclosed |
| EP-2521613-A1 | SCALABLE PRODUCTION OF PRECISION HYDROCARBONS FROM TRIALKYLALUMINUM VIA TERNARY LIVING COORDINATIVE CHAIN TRANSFER POLYMERIZATION | University of Maryland, College Park (US) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011082418-A1 | SCALABLE PRODUCTION OF PRECISION HYDROCARBONS FROM TRIALKYLALUMINUM VIA TERNARY LIVING COORDINATIVE CHAIN TRANSFER POLYMERIZATION | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2011-07-07 | — | — | WO | disclosed |
| US-20110028654-A1 | Process for Preparation of Polyolefins Via Living Coordinative Chain Transfer Polymerization | UNIVERSITY OF MARYLAND, COLLEGE PARK OFFICE OF TECHNOLOGY COMMERCIALIZATION (US) | 2011-02-03 | — | — | US | disclosed |
| EP-2220128-A1 | PROCESS FOR PREPARATION OF POLYOLEFINS VIA LIVING COORDINATIVE CHAIN TRANSFER POLYMERIZATION | University of Maryland, College Park (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009061499-A1 | PROCESS FOR PREPARATION OF POLYOLEFINS VIA LIVING COORDINATIVE CHAIN TRANSFER POLYMERIZATION | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2009-05-14 | — | — | WO | disclosed |
| WO-2003008459-A9 | METHOD FOR PRODUCTION OF MULTIMODAL POLYOLEFINS OF TUNABLE COMPOSITION, MOLECULAR WEIGHT, AND POLYDISPERSITY | UNIV MARYLAND (US) | 2003-10-16 | — | — | WO | disclosed |
| WO-2003008459-A1 | METHOD FOR PRODUCTION OF MULTIMODAL POLYOLEFINS OF TUNABLE COMPOSITION, MOLECULAR WEIGHT, AND POLYDISPERSITY | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2003-01-30 | — | — | WO | disclosed |
| US-6214946-B1 | GAS PHASE ETHYLENE-PROPYLENE-DIENE RUBBER PRODUCTION EMPLOYING AN INERT PARTICULATE MATERIAL (WHICH IS PASSIVATED BY PRETREATMENT WITH TRIALKYLALUMINUM COMPOUND), AND A SINGLE-SITE (E.G., METALLOCENE) CATALYST. | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2001-04-10 | — | — | US | disclosed |
| US-6166154-A | Olefin polymerization catalyst composition having increased activity | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| EP-1054025-A1 | Method for controlling molecular weight and molecular weight distribution in polymers produced using a single site catalyst | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-11-22 | — | — | EP | disclosed |
| EP-1054024-A1 | Inert particulate material passivation for single-site catalyst in EPDM production | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-11-22 | — | — | EP | disclosed |
| US-6136747-A | SOLID ZIEGLER-NATTA CATALYST; A LIQUID SINGLE SITE CATALYST; AND AT LEAST ONE ACTIVATING COCATALYST IS PROVIDED. POLYMERS HAVING A BROAD OR BIMODAL MOLECULAR WEIGHT DISTRIBUTION MAY BE MADE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-10-24 | — | — | US | disclosed |
| EP-0965601-A1 | Mixed catalyst composition for the production of olefin polymers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0942009-A2 | Reduced sheeting in single-site and single-site like polymerization by employing a chromium containing compound | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (a Delaware corporation) (US) | 1999-09-15 | — | — | EP | disclosed |
| US-5912202-A | CONTACTING OUTSIDE OF POLYMERIZATION REACTOR A SINGLE SITE CATALYST PRECURSOR WITH AN ACTIVATING COCATALYST BEFORE, DURING, OR AFTER CONTACTING THE SINGLE SITE CATALYST PRECURSOR WITH A WEAKLY COORDINATING ELECTRON DONOR SUCH AS 1-HEXENE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109900-A1 | Scalable Production of Precision Hydrocarbons from Trialkylaluminum via Ternary Living Coordinative Chain Transfer Polymerization | TRMT1L, CD40LG, APOL1 | PNMT 1638/4885NPC1 1690/4885RAB9A 4673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.