Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19833730 | 0.89 | CHRNA7 (0.53) | GPR119SCN9ACHRNA7RORCTACR1 | |
| SCHEMBL21381923 | 0.88 | MRGPRX4 (0.46) | GPR119SCN9ARORC | |
| SCHEMBL21381584 | 0.85 | CHRNA7 (0.46) | SCN9ACHRNA7 | |
| SCHEMBL21723050 | 0.83 | MGLL (0.51) | GPR119RORCTACR1PLK1MAPT | |
| SCHEMBL21381651 | 0.81 | CHRNA7 (0.41) | GPR119SCN9ACHRNA7 | |
| SCHEMBL2154224 | 0.80 | USP30 (0.44) | GPR119SCN9ANAMPTLIPEPDE4B | |
| SCHEMBL23850247 | 0.78 | GPR119 (0.49) | GPR119SCN9ACHRNA7RORCTACR1 | |
| SCHEMBL23091766 | 0.77 | GPR119 (0.48) | GPR119RORCTACR1MAPTLIPE | |
| SCHEMBL23211881 | 0.77 | RORC (0.42) | GPR119RORCTACR1MAPTPDE4B | |
| SCHEMBL21723071 | 0.77 | RBP4 (0.49) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768684-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2021-01-27 | — | — | EP | disclosed |
| WO-2019180185-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2019-09-26 | — | — | WO | disclosed |