SCHEMBL21382898

SCHEMBL21382898

Brc1ccc2c3c(cccc13)Sc1ccccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
CYP1B1 Q16678 13/20 0.44
HKDC1 Q2TB90 1/20 0.39
ALDH1A1 P00352 2/20 0.38
POLB P06746 2/20 0.38
RXFP1 Q9HBX9 1/20 0.38
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
PABPC1 P11940 1/20 0.38
KMT2A Q03164 1/20 0.38
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
TP53 P04637 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31301078 1.00 CYP1A2 (0.47) CYP1A2CYP1B1HKDC1ALDH1A1POLB
SCHEMBL24575488 0.96 CYP1A2 (0.44) CYP1A2CYP1B1HKDC1ALDH1A1POLB
SCHEMBL16558472 0.85 CRHBP (0.41) CYP1A2ALDH1A1POLBKDM4EMEN1
SCHEMBL16558474 0.83 CRHBP (0.39) CYP1A2ALDH1A1POLBKDM4EMEN1
SCHEMBL18012107 0.80 CRHBP (0.37) CYP1A2ALDH1A1KDM4EMAPTPABPC1
SCHEMBL16558545 0.79 SLC6A3 (0.34) CYP1A2HKDC1ALDH1A1LMNAKDM4E
SCHEMBL24575614 0.79 LMNA (0.39) CYP1A2CYP1B1HKDC1LMNAMEN1
SCHEMBL21385050 0.79 GABRG2 (0.33) CYP1A2HKDC1ALDH1A1RXFP1KDM4E
SCHEMBL31301080 0.79 GABRG2 (0.33) CYP1A2HKDC1ALDH1A1RXFP1KDM4E
SCHEMBL24575569 0.79 KDM4E (0.47) CYP1A2ALDH1A1POLBLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021132952-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND DISPLAY DEVICE 에스케이머티리얼즈 주식회사 2021-07-01 WO disclosed
WO-2021125622-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND DISPLAY DEVICE 에스케이머티리얼즈 주식회사 2021-06-24 WO disclosed
WO-2019182360-A1 COMPOUND, ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY DEVICE 에스케이머티리얼즈 주식회사 2019-09-26 WO disclosed