Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28553382 | 0.82 | SRC (0.45) | GSRDPP7DPP8DPP9MMP2 | |
| SCHEMBL17202311 | 0.82 | MMP2 (0.51) | GSRDPP7DPP8DPP9MMP2 | |
| SCHEMBL1537425 | 0.82 | MMP2 (0.58) | GSRDPP7DPP8DPP9MMP2 | |
| SCHEMBL237821 | 0.82 | MMP2 (0.58) | GSRDPP7DPP8DPP9MMP2 | |
| Mandelic Acid SCHEMBL21383946 | 0.82 | GSR (0.62) | GSRDPP7DPP8DPP9MMP2 | |
| SCHEMBL10773507 | 0.81 | KIF11 (0.53) | GSRDPP7DPP8DPP9MMP2 | |
| SCHEMBL1404247 | 0.80 | GSR (0.61) | GSRDPP7DPP8DPP9 | |
| SCHEMBL20240364 | 0.80 | GSR (0.61) | GSRDPP7DPP8DPP9 | |
| SCHEMBL344574 | 0.80 | GSR (0.61) | GSRDPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL2099474 | 0.79 | GSR (0.59) | GSRDPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183385-A1 | MAPK/ERK INHIBITION FOR OVARIAN AND OTHER CANCERS | UNIVERSITY OF ROCHESTER (US) | 2019-09-26 | — | — | WO | disclosed |