Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29381825 | 0.89 | LOXL2 (0.47) | LOXL2LMNAALDH1A1KDM4EF2 | |
| SCHEMBL11499532 | 0.85 | ADRB2 (0.48) | PBRM1ADRB2ADRB1ADRB3CHRNB2 | |
| SCHEMBL8003710 | 0.85 | PBRM1 (0.59) | PBRM1ADRB2ADRB1ADRB3CHRNB2 | |
| SCHEMBL29071827 | 0.82 | PBRM1 (0.55) | PBRM1ADRB2ADRB1ADRB3CHRNB2 | |
| SCHEMBL28539853 | 0.82 | PBRM1 (0.55) | PBRM1ADRB2ADRB1ADRB3CHRNB2 | |
| SCHEMBL9950105 | 0.80 | PBRM1 (0.53) | PBRM1ADRB2ADRB1ADRB3CHRNB2 | |
| SCHEMBL9701403 | 0.80 | PBRM1 (0.63) | PBRM1ADRB2ADRB1ADRB3CHRNB2 | |
| SCHEMBL4654816 | 0.80 | LOXL2 (0.53) | PBRM1ADRB2ADRB1ADRB3CHRNB2 | |
| SCHEMBL186246 | 0.80 | LMNA (0.52) | NPC1LMNAPOLBALDH1A1KDM4E | |
| SCHEMBL1417358 | 0.79 | PBRM1 (0.52) | PBRM1ADRB2ADRB1ADRB3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182070-A1 | LIQUID CRYSTAL ALIGNING AGENT, POLYMER FOR OBTAINING SAME, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | 日産化学株式会社 | 2019-09-26 | — | — | WO | disclosed |