Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MITF | O75030 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5824157 | 0.90 | KMT2A (0.49) | KMT2AALDH1A1MITFLMNAHTT | |
| SCHEMBL1168220 | 0.84 | IDO1 (0.52) | KMT2AALDH1A1MITFLMNAHTT | |
| SCHEMBL4784858 | 0.80 | ALDH1A1 (0.44) | KMT2AALDH1A1MITFLMNAHTT | |
| SCHEMBL7702093 | 0.79 | ADRB2 (0.47) | KMT2AALDH1A1MITFLMNAHTT | |
| SCHEMBL2492695 | 0.77 | MEN1 (0.45) | KMT2AALDH1A1MITFLMNAHTT | |
| SCHEMBL11316134 | 0.76 | HTT (0.45) | KMT2AALDH1A1MITFLMNAHTT | |
| SCHEMBL564626 | 0.76 | GABRA1 (0.48) | KMT2AALDH1A1MITFLMNAHTT | |
| SCHEMBL1485712 | 0.75 | MAPT (0.59) | KMT2AALDH1A1MITFLMNAHTT | |
| SCHEMBL796531 | 0.75 | KMT2A (0.48) | KMT2AALDH1A1MITFLMNAHTT | |
| SCHEMBL26064904 | 0.74 | CA12 (0.41) | KMT2AALDH1A1MITFLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10421738-B2 | Chiral cyclodecynes and methods | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2019-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10421738-B2 | Chiral cyclodecynes and methods | CYP8B1, CYCS, CYP51A1 | KMT2A 2805/4885ALDH1A1 917/4885MITF 3625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.