Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18269958 | 1.00 | ALDH1A1 (0.38) | ALDH1A1LMNANAAACYP3A4TDP1 | |
| SCHEMBL1993331 | 0.92 | ALDH1A1 (0.41) | ALDH1A1LMNACYP3A4TDP1ADRA2A | |
| SCHEMBL29305748 | 0.92 | GRM5 (0.35) | ALDH1A1LMNANAAACYP1A2 | |
| SCHEMBL21386559 | 0.85 | GRM5 (0.35) | ALDH1A1LMNANAAACYP1A2 | |
| SCHEMBL945304 | 0.84 | NPC1 (0.46) | ALDH1A1LMNACYP3A4TDP1ADRA2A | |
| SCHEMBL30421135 | 0.84 | NPC1 (0.46) | ALDH1A1LMNACYP3A4TDP1ADRA2A | |
| SCHEMBL29305779 | 0.84 | CYP3A4 (0.35) | ALDH1A1LMNACYP3A4ADRA2ANPC1 | |
| SCHEMBL14207004 | 0.82 | NAAA (0.36) | ALDH1A1LMNANAAAARCYP1A2 | |
| SCHEMBL12011023 | 0.82 | NAAA (0.36) | ALDH1A1LMNANAAAARCYP1A2 | |
| SCHEMBL29305752 | 0.81 | FFAR1 (0.32) | ALDH1A1LMNACYP3A4ADRA2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-11739265-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| EP-3739020-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-08-23 | — | — | EP | disclosed |
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
| WO-2022128845-A1 | HETEROAROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |
| US-11306251-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2022-04-19 | — | — | US | disclosed |
| US-11268026-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2022-03-08 | — | — | US | disclosed |
| WO-2022043376-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2022-03-03 | — | — | WO | disclosed |
| WO-2021116080-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2021-06-17 | — | — | WO | disclosed |
| EP-3739020-A1 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2020-11-18 | — | — | EP | disclosed |
| US-20200347301-A1 | Isothiocyanato-tolanes | MERCK PATENT GMBH (DE) | 2020-11-05 | — | — | US | disclosed |
| EP-3733816-A1 | ISOTHIOCYANATO-TOLANES | Merck Patent GmbH (DE) | 2020-11-04 | — | — | EP | disclosed |
| EP-3543313-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2020-10-07 | — | — | EP | disclosed |
| EP-3543314-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2020-09-09 | — | — | EP | disclosed |
| US-20190352564-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-11-21 | — | — | US | disclosed |
| US-20190292458-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| US-20190292460-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| EP-3543314-A1 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2019-09-25 | — | — | EP | disclosed |
| EP-3543313-A1 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2019-09-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, TRPC1, CRY1 | ALDH1A1 1864/4885LMNA 2735/4885NAAA 3756/4885 |
| US-20230025385-A1 | FLUORINATED AROMATIC COMPOUNDS | TRPA1, FOXM1, AFF1 | ALDH1A1 1136/4885LMNA 2980/4885NAAA 3881/4885 |
| US-11739265-B2 | Aromatic isothiocyanates | TRPA1, CRY1, FOXM1 | ALDH1A1 1554/4885LMNA 4099/4885NAAA 3694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.