Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 4/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21387779 | 0.85 | QPCT (0.38) | QPCTQPCTLKDRTDO2KDM4E | |
| SCHEMBL21565690 | 0.78 | QPCT (0.36) | KDM5BQPCTQPCTLTDO2KDM4E | |
| SCHEMBL21565693 | 0.76 | KDM5B (0.37) | KDM5BQPCTQPCTLPIK3CDPIK3CA | |
| SCHEMBL23123086 | 0.75 | QPCT (0.51) | QPCTQPCTLTDO2KDM4EALDH1A1 | |
| SCHEMBL21565626 | 0.73 | ABL1 (0.51) | PIK3CDPIK3CAPIK3CBMTORPIK3CG | |
| SCHEMBL25912031 | 0.72 | QPCT (0.39) | KDM5BQPCTQPCTLKDM4EALDH1A1 | |
| SCHEMBL6008269 | 0.72 | MAPT (0.50) | QPCTQPCTLKDM4EALDH1A1MAPT | |
| SCHEMBL31143361 | 0.72 | MAPT (0.50) | QPCTQPCTLKDM4EALDH1A1MAPT | |
| SCHEMBL21387732 | 0.71 | BRD4 (0.40) | KDM5BQPCTQPCTLKDRKDM4E | |
| SCHEMBL2810219 | 0.71 | QPCT (0.41) | QPCTQPCTLKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190343802-A1 | CELL-PROTECTIVE COMPOUNDS AND THEIR USE | ETH Zürich (CH) | 2019-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190343802-A1 | CELL-PROTECTIVE COMPOUNDS AND THEIR USE | SRPK2, SRSF2, SRPK1 | KDM5B 4578/4885QPCT 4373/4885QPCTL 4255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.