Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 4/20 | 0.86 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL28186303 | 0.97 | SLC22A1 (0.80) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL2138786 | 0.97 | SLC22A1 (0.80) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL28143245 | 0.97 | SLC22A1 (0.80) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL28294190 | 0.96 | SLC22A1 (0.92) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL29026657 | 0.96 | SLC22A1 (0.92) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL21980 | 0.96 | SLC22A1 (0.92) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL4859378 | 0.96 | SLC22A1 (0.92) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL25332097 | 0.93 | SLC22A1 (0.86) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL21525927 | 0.93 | SLC22A1 (0.86) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL2138792 | 0.93 | SLC22A1 (0.86) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106693912-A | Adsorbent for capturing carbon dioxide as well as preparation method and application of adsorbent | 太原理工大学 | 2017-05-24 | — | — | CN | claimed |
| CN-105233859-A | Fischer-Tropsch synthesis catalyst in core-shell structure and preparation method therefor | SHANXI LU AN MINING GROUP CO | 2016-01-13 | — | — | CN | claimed |
| CN-103920530-B | The preparation method of 2-hydroxyl-5-alkylacetophenone oxime and used catalyst | SICHUAN ZHIJIANG ADVANCED MATERIALS CO., LTD. (CN) | 2015-12-09 | — | — | CN | claimed |
| CN-104549448-A | Method for producing light steam cracking raw materials by catalytic cracking | CHINA PETROLEUM & CHEMICAL | 2015-04-29 | — | — | CN | claimed |
| CN-104549440-A | Adhesive-free oxy-compound aromatization catalyst and preparation method thereof | CHINA PETROLEUM & CHEMICAL | 2015-04-29 | — | — | CN | claimed |
| CN-103920530-A | Preparation method for 2-hydroxy-5-alkylbenzene acetophenone and used catalyst in preparation method | SICHUAN ZHIJIANG ADVANCED MATERIALS CO LTD | 2014-07-16 | — | — | CN | claimed |
| CN-101857774-B | Polishing composition for improving chemical-mechanical polishing rate of silicon substrate and application thereof | SHANGHAI INST MICROSYS & INF | 2013-12-25 | — | — | CN | claimed |
| CN-101920194-A | Effective method for improving photocatalysis efficiency of nano TiO2 catalyst | UNIV NANKAI | 2010-12-22 | — | — | CN | claimed |
| CN-101857774-A | Polishing composition for improving chemical-mechanical polishing rate of silicon substrate and application thereof | SHANGHAI INST MICROSYS & INF | 2010-10-13 | — | — | CN | claimed |
| EP-2980103-B1 | LOW MOLECULAR WEIGHT GLYCOSAMINOGLYCAN DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | JIUZHITANG CO LTD (CN) | 2020-11-04 | — | — | EP | disclosed |
| US-10615054-B2 | Method for manufacturing conductive line | UNIMICRON TECHNOLOGY CORP. (TW) | 2020-04-07 | — | — | US | disclosed |
| CN-109928397-A | A kind of monodisperse silica microspheres and preparation method thereof | 深圳迈思瑞尔科技有限公司 | 2019-06-25 | — | — | CN | disclosed |
| CN-109844035-A | Method for producing organic pigment composition, method for producing coating film, and method for evaluating brightness of coating film | M技术株式会社 | 2019-06-04 | — | — | CN | disclosed |
| US-20190109017-A1 | METHOD FOR MANUFACTURING CONDUCTIVE LINE | UNIMICRON TECHNOLOGY CORP. (TW) | 2019-04-11 | — | — | US | disclosed |
| WO-2008125465-A1 | METHOD FOR REMOVING COLOR FROM POLYMERIC MATERIAL | BASF SE (CH) | 2008-10-23 | — | — | WO | disclosed |
| US-20080255259-A1 | Method for removing color from polymeric material | BASF SE (DE) | 2008-10-16 | — | — | US | disclosed |
| CN-101205480-A | Non-hydrogenation method for lowering sulfur content of oil products | CHINA PETROLEUM & CHEMICAL (CN) | 2008-06-25 | — | — | CN | disclosed |
| CN-100375650-C | Low temperature process of preparing carbon-doped mesoporous TiO2 visible light catalyst | UNIV CENTRAL CHINA NORMAL (CN) | 2008-03-19 | — | — | CN | disclosed |
| CN-1857769-A | Low temperature process of preparing carbon-doped mesoporous TiO2 visible light catalyst | UNIV CENTRAL CHINA NORMAL (CN) | 2006-11-08 | — | — | CN | disclosed |
| CN-1827666-A | Conjugated polymer containing sulfonic group substituted triarylamine and use thereof | UNIV SOUTH CHINA TECH (CN) | 2006-09-06 | — | — | CN | disclosed |