Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 4/20 | 0.92 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.79 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL28294190 | 1.00 | SLC22A1 (0.92) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL29026657 | 1.00 | SLC22A1 (0.92) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Water SCHEMBL3484887 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Water SCHEMBL3485332 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL2138783 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL23202726 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL20503801 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL21525929 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL21525927 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL9416676 | 0.96 | SLC22A1 (0.86) | SLC22A1SLC22A2TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 48580 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260150612-A1 | SURFACE CONDITIONING PROCESSES FOR SEMICONDUCTOR PROCESSING CHAMBER PARTS | APPLIED MATERIALS, INC (US) | 2026-05-28 | — | — | US | claimed |
| EP-4747300-A1 | ON-SUBSTRATE MIXING | NANIZE AS (NO) | 2026-05-27 | — | — | EP | claimed |
| US-12638771-B2 | Photoresist, method of manufacturing a semiconductor device and method of extreme ultraviolet lithography | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2026-05-26 | — | — | US | claimed |
| CN-122076380-A | Hollow mesoporous HZSM-5 carbon dioxide adsorption material based on metal-organic amine synergistic effect, and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122077957-A | LCP film assembly and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-118908237-B | Super cage Na with high proportion+FAU molecular sieve for exchange position and application of FAU molecular sieve to adsorption separation of fluorine-containing electronic gas | JIANG University OF TECHNOLOGY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-116940556-B | Process for preparing amidines | VERSALIS S.P.A. (IT) | 2026-05-26 | — | — | CN | claimed |
| CN-122079877-A | Industrial preparation method of 2-hydroxy-6- (trifluoromethyl) pyridine | — | 2026-05-26 | — | — | CN | claimed |
| CN-122082124-A | Semiconductor surface treating agent and application thereof, and silicon carbide laser modified layer stripping method | — | 2026-05-26 | — | — | CN | claimed |
| CN-117623292-B | Method for preparing graphene nanosheets by electrochemical cathode stripping and application of graphene nanosheets | DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2026-05-26 | — | — | CN | claimed |
| US-4237053-A | Total synthesis of the utero-evacuant substance d,l-zoapatanol | ORTHO PHARMACEUTICAL CORPORATION (US) | 1980-12-02 | — | — | US | claimed |
| US-4209643-A | Preparation of acetals | ETHYL CORPORATION (US) | 1980-06-24 | — | — | US | claimed |
| US-4192820-A | Preparation of 3-methyl-2-buten-1-al | BASF AKTIENGESELLSCHAFT (DE) | 1980-03-11 | — | — | US | claimed |
| US-4169960-A | REMOVING WATER FROM FLUORINATED ALCOHOLS EMPLOYING A TETRAHYDROCARBYLAMMONIUM HYDROXIDE | PHILLIPS PETROLEUM COMPANY (US) | 1979-10-02 | — | — | US | claimed |
| EP-0002872-A1 | Process for preparing acylated esters of hydroxy carboxylates | THE PROCTER & GAMBLE COMPANY (US) | 1979-07-11 | — | — | EP | claimed |
| US-4159287-A | GRAFT POLYMER WITH POLYPIVALOLACTONE | EASTMAN KODAK COMPANY (US) | 1979-06-26 | — | — | US | claimed |
| US-4133826-A | REACTION OF OPTICALLY ACTIVE OR RACEMIC MIXTURE OF ESTERS WITH BASE | ROUSSEL UCLAF (FR) | 1979-01-09 | — | — | US | claimed |
| US-4127497-A | Michael adducts of (substituted) cyclopentadiene and esters: a process therefor and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1978-11-28 | — | — | US | claimed |
| US-4092306-A | Oxidation of hydrazones to the corresponding diazo compounds in the presence of a phase transfer and an oxidation catalyst which is iodine, an iodide or an iodonium salt | GLAXO LABORATORIES LIMITED (EN) | 1978-05-30 | — | — | US | claimed |
| US-3978137-A | OXIDATION OF SULFUR-CONTAINING COMPOUNDS | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-08-31 | — | — | US | claimed |