Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390711 | 0.83 | CYP11B2 (0.32) | CYP11B1CYP11B2SMN1; SMN2ALDH1A1AGTR1 | |
| SCHEMBL21391124 | 0.82 | HTR3E (0.35) | CYP11B2SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL21390999 | 0.81 | JAK1 (0.34) | RORCSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL21391001 | 0.80 | ALDH1A1 (0.32) | RORCSMN1; SMN2ALDH1A1 | |
| SCHEMBL21390782 | 0.79 | RORC (0.30) | RORC | |
| SCHEMBL19278031 | 0.79 | RORC (0.42) | ALKNTRK1INSRLCKLTK | |
| SCHEMBL21390955 | 0.78 | ALDH1A1 (0.32) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL21391141 | 0.76 | RORC (0.32) | RORC | |
| SCHEMBL21391000 | 0.76 | PTGDR2 (0.33) | GNRHRMEN1KMT2AAGTR1AGTR2 | |
| SCHEMBL21390907 | 0.75 | RORC (0.32) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |