Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390671 | 0.90 | — | — | |
| SCHEMBL21391179 | 0.85 | ACSS2 (0.33) | — | |
| SCHEMBL21390820 | 0.83 | ACSS2 (0.33) | — | |
| SCHEMBL21390888 | 0.82 | LPAR1 (0.31) | HCRTR2 | |
| SCHEMBL21391083 | 0.79 | — | — | |
| SCHEMBL21390961 | 0.79 | — | — | |
| SCHEMBL21390958 | 0.79 | — | — | |
| SCHEMBL21390896 | 0.78 | AGTR1 (0.31) | — | |
| SCHEMBL21390957 | 0.77 | NTRK1 (0.33) | HCRTR2 | |
| SCHEMBL21390927 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |