Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30315769 | 0.92 | ACSS2 (0.32) | — | |
| SCHEMBL21354736 | 0.92 | ACSS2 (0.32) | — | |
| SCHEMBL18791929 | 0.84 | ACSS2 (0.38) | — | |
| SCHEMBL20111113 | 0.84 | ACSS2 (0.38) | — | |
| SCHEMBL18791928 | 0.84 | ACSS2 (0.38) | — | |
| SCHEMBL19278076 | 0.83 | LMNA (0.32) | HCRTR2 | |
| SCHEMBL19278082 | 0.83 | LMNA (0.32) | HCRTR2 | |
| SCHEMBL18791653 | 0.82 | ACSS2 (0.35) | — | |
| SCHEMBL20111100 | 0.82 | ACSS2 (0.35) | — | |
| SCHEMBL21390812 | 0.82 | PDE4A (0.30) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |