Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390815 | 0.92 | HDAC1 (0.33) | JAK1 | |
| SCHEMBL21390691 | 0.76 | — | — | |
| SCHEMBL21390704 | 0.74 | — | — | |
| SCHEMBL21391078 | 0.73 | KDM4E (0.33) | JAK1 | |
| SCHEMBL21391079 | 0.73 | CYP19A1 (0.32) | JAK1 | |
| SCHEMBL21390979 | 0.71 | HDAC1 (0.32) | JAK1 | |
| SCHEMBL21390808 | 0.71 | JAK2 (0.33) | JAK1 | |
| SCHEMBL21391080 | 0.71 | CDK4 (0.31) | — | |
| SCHEMBL21390810 | 0.70 | CYP19A1 (0.32) | JAK1 | |
| SCHEMBL23132031 | 0.70 | CYP11B2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |