Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390893 | 0.97 | RORC (0.31) | RORC | |
| SCHEMBL21390691 | 0.90 | — | — | |
| SCHEMBL21390810 | 0.82 | CYP19A1 (0.32) | RORC | |
| SCHEMBL21391079 | 0.79 | CYP19A1 (0.32) | RORC | |
| SCHEMBL21391108 | 0.77 | CACNA1H (0.36) | RORC | |
| SCHEMBL21390935 | 0.77 | HDAC1 (0.33) | RORC | |
| SCHEMBL21391103 | 0.75 | HDAC1 (0.33) | — | |
| SCHEMBL21390898 | 0.75 | HDAC1 (0.32) | — | |
| SCHEMBL21390826 | 0.75 | CACNA1H (0.35) | — | |
| SCHEMBL21391164 | 0.75 | CDK4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |