Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390972 | 1.00 | PDE4B (0.39) | PDE4BPDE4DTP53ALDH1A1TSHR | |
| SCHEMBL21390985 | 0.93 | PDE4B (0.39) | PDE4BPDE4DTP53ALDH1A1TSHR | |
| SCHEMBL21390941 | 0.85 | CYP11B2 (0.33) | — | |
| SCHEMBL16084482 | 0.80 | PDE4B (0.44) | PDE4BPDE4DTP53ALDH1A1TSHR | |
| SCHEMBL16084150 | 0.80 | PDE4B (0.44) | PDE4BPDE4DTP53ALDH1A1TSHR | |
| SCHEMBL16084140 | 0.80 | PDE4B (0.44) | PDE4BPDE4DTP53ALDH1A1TSHR | |
| SCHEMBL21390980 | 0.80 | PDE4B (0.38) | PDE4BPDE4DTP53ALDH1A1TSHR | |
| SCHEMBL21390944 | 0.79 | OPRM1 (0.41) | PDE4BPDE4DTP53ALDH1A1TSHR | |
| SCHEMBL16084149 | 0.75 | PDE4B (0.45) | PDE4BPDE4DTP53ALDH1A1TSHR | |
| SCHEMBL21390943 | 0.74 | LMNA (0.46) | PDE4BPDE4DTP53ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |