Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390992 | 0.85 | PDE4B (0.39) | — | |
| SCHEMBL21390972 | 0.85 | PDE4B (0.39) | — | |
| SCHEMBL16084327 | 0.80 | CYP11B2 (0.34) | CYP11B2PDE10APIK3CAMTOR | |
| SCHEMBL21391130 | 0.80 | CYP11B2 (0.38) | CYP11B2PDE10APIK3CAMTOR | |
| SCHEMBL21391131 | 0.80 | CYP11B2 (0.37) | CYP11B2PDE10APIK3CAMTOR | |
| SCHEMBL21390985 | 0.78 | PDE4B (0.39) | — | |
| SCHEMBL21391073 | 0.76 | PDE10A (0.37) | CYP11B2PDE10APIK3CAMTOR | |
| SCHEMBL21391072 | 0.75 | PDE10A (0.34) | CYP11B2PDE10APIK3CAMTOR | |
| SCHEMBL21391070 | 0.74 | CYP11B2 (0.36) | CYP11B2PDE10APIK3CAMTOR | |
| SCHEMBL21391124 | 0.74 | HTR3E (0.35) | CYP11B2PDE10APIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |