Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391106 | 0.83 | HDAC1 (0.37) | ACSS2 | |
| SCHEMBL21391117 | 0.81 | POLB (0.31) | APEX1 | |
| SCHEMBL21354727 | 0.79 | ACSS2 (0.38) | ACSS2S1PR1 | |
| SCHEMBL21390842 | 0.76 | HDAC1 (0.36) | ACSS2 | |
| SCHEMBL21391031 | 0.73 | — | — | |
| SCHEMBL21391014 | 0.71 | MCHR1 (0.35) | S1PR1 | |
| SCHEMBL21390879 | 0.71 | MCHR1 (0.35) | S1PR1 | |
| SCHEMBL21390845 | 0.70 | HDAC1 (0.40) | ACSS2 | |
| SCHEMBL21390928 | 0.69 | HPGDS (0.36) | — | |
| SCHEMBL21354717 | 0.68 | CSNK1D (0.46) | ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |