Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21354721 | 0.79 | CXCR6 (0.33) | TAS1R3TAS1R1TAS1R2CXCR6 | |
| SCHEMBL21390947 | 0.78 | — | — | |
| SCHEMBL21390857 | 0.75 | RORC (0.32) | — | |
| SCHEMBL21391176 | 0.75 | HDAC1 (0.32) | — | |
| SCHEMBL21391164 | 0.74 | CDK4 (0.35) | — | |
| SCHEMBL21391174 | 0.72 | JAK1 (0.35) | — | |
| SCHEMBL21391073 | 0.71 | PDE10A (0.37) | — | |
| SCHEMBL21390679 | 0.71 | TNF (0.36) | — | |
| SCHEMBL21390682 | 0.71 | JAK1 (0.32) | — | |
| SCHEMBL21390826 | 0.70 | CACNA1H (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |