Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.32 |
| ▸ | BRD4 | O60885 | 7/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391168 | 0.86 | RORC (0.35) | HDAC1 | |
| SCHEMBL21391171 | 0.81 | BRD4 (0.39) | HDAC1BRD4 | |
| SCHEMBL21391164 | 0.78 | CDK4 (0.35) | HDAC1BRD4CREBBP | |
| SCHEMBL18779260 | 0.78 | EGFR (0.34) | BRD4CREBBP | |
| SCHEMBL21391177 | 0.76 | RORC (0.32) | HDAC1 | |
| SCHEMBL21390857 | 0.75 | RORC (0.32) | — | |
| SCHEMBL21391047 | 0.75 | PIM1 (0.30) | — | |
| SCHEMBL21390781 | 0.74 | BRD4 (0.33) | BRD4CREBBP | |
| SCHEMBL21391073 | 0.73 | PDE10A (0.37) | — | |
| SCHEMBL21354612 | 0.73 | KCNQ3 (0.36) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |