Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 13/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390681 | 0.88 | BRD4 (0.35) | PPARGGRM2PLA2G10PLA2G2ABRD4 | |
| SCHEMBL23132028 | 0.85 | BRD4 (0.35) | PPARGPLA2G10PLA2G2ABRD4 | |
| SCHEMBL21391179 | 0.85 | ACSS2 (0.33) | ACSS2PPARGGRM2 | |
| SCHEMBL21390928 | 0.83 | HPGDS (0.36) | — | |
| SCHEMBL21390820 | 0.82 | ACSS2 (0.33) | ACSS2PPARG | |
| SCHEMBL21391160 | 0.81 | ACSS2 (0.38) | ACSS2 | |
| SCHEMBL21391173 | 0.80 | ACSS2 (0.36) | ACSS2 | |
| SCHEMBL21354556 | 0.80 | ACSS2 (0.42) | ACSS2 | |
| SCHEMBL21390993 | 0.77 | HTT (0.31) | ACSS2 | |
| SCHEMBL21391167 | 0.77 | PPARG (0.40) | PPARGPLA2G10PLA2G2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |